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3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
mammalian protein found in Mus musculus
3-hydroxy-3-methylglutaryl coenzyme A synthase
Hmgcs2
HMG-CoA synthase
hydroxymethylglutaryl-CoA synthase, mitochondrial
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P54869
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
P54869
part of
Thiolase-like
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P54869
Hydroxymethylglutaryl-CoA synthase, eukaryotic
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P54869
Hydroxymethylglutaryl-coenzyme A synthase, N-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Hydroxymethylglutaryl-coenzyme A synthase, active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P54869
encoded by
Hmgcs2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P54869
molecular function
transferase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P54869
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IEA
catalytic activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IEA
hydroxymethylglutaryl-CoA synthase activity
determination method
IEA
IDA
3 references
retrieved
16 September 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P54869
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54869&geneProductId=UniProtKB:P54869
determination method
IEA
retrieved
16 September 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54869&geneProductId=UniProtKB:P54869
determination method
IEA
retrieved
16 September 2017
stated in
SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks
GOA
curator
UniProt
UniProt protein ID
P54869
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54869&geneProductId=UniProtKB:P54869
determination method
IDA
hydroxymethylglutaryl-CoA synthase activity
determination method
IBA
IDA
IEA
ISO
5 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P54869
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IEA
retrieved
14 February 2019
stated in
SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks
GOA
curator
UniProt
UniProt protein ID
P54869
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IBA
cell component
mitochondrion
determination method
IDA
IEA
ISO
6 references
retrieved
16 September 2017
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54869&geneProductId=UniProtKB:P54869
determination method
ISO
retrieved
16 September 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P54869
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54869&geneProductId=UniProtKB:P54869
determination method
IEA
retrieved
16 September 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54869&geneProductId=UniProtKB:P54869
determination method
IEA
retrieved
16 September 2017
stated in
Nutritional stress exacerbates hepatic steatosis induced by deletion of the histidine nucleotide-binding (Hint2) mitochondrial protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54869&geneProductId=UniProtKB:P54869
determination method
IDA
retrieved
16 September 2017
stated in
A mitochondrial protein compendium elucidates complex I disease biology
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54869&geneProductId=UniProtKB:P54869
determination method
IDA
retrieved
16 September 2017
stated in
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54869&geneProductId=UniProtKB:P54869
determination method
IDA
mitochondrial inner membrane
determination method
IDA
1 reference
retrieved
16 September 2017
stated in
Proteomic analysis of the mouse liver mitochondrial inner membrane
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54869&geneProductId=UniProtKB:P54869
determination method
IDA
mitochondrion
determination method
HDA
IBA
IDA
IEA
ISO
7 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P54869
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IEA
retrieved
14 February 2019
stated in
Nutritional stress exacerbates hepatic steatosis induced by deletion of the histidine nucleotide-binding (Hint2) mitochondrial protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IBA
retrieved
14 February 2019
stated in
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
HDA
retrieved
14 February 2019
stated in
A mitochondrial protein compendium elucidates complex I disease biology
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
HDA
mitochondrial inner membrane
determination method
HDA
1 reference
retrieved
14 February 2019
stated in
Proteomic analysis of the mouse liver mitochondrial inner membrane
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
HDA
mitochondrial matrix
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
ISO
biological process
steroid metabolic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P54869
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IEA
sterol biosynthetic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P54869
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IEA
lipid metabolism
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P54869
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IEA
cholesterol metabolic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P54869
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IEA
isoprenoid biosynthetic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IEA
cholesterol biosynthetic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P54869
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IEA
metabolism
determination method
IEA
1 reference
retrieved
16 September 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54869&geneProductId=UniProtKB:P54869
determination method
IEA
steroid biosynthetic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P54869
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IEA
acetyl-CoA metabolic process
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IBA
farnesyl diphosphate biosynthetic process, mevalonate pathway
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54869
determination method
IBA
has part(s)
Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P54869
Hydroxymethylglutaryl-coenzyme A synthase, active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P54869
Hydroxymethylglutaryl-coenzyme A synthase, N-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P54869
Identifiers
RefSeq protein ID
NP_032282
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
15360
UniProt protein ID
P54869
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P54869
Ensembl protein ID
ENSMUSP00000088249
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000088249
ENSMUSP00000113296
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000113296
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