(Q21499065)

http://www.ebi.ac.uk/interpro/protein/Q6NXK8

Epithelial sodium channel, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

sodium channel activity

acid-sensing ion channel activity

2 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

14 February 2019

Subunit-specific inhibition of acid sensing ion channels by stomatin-like protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

1 reference

14 February 2019

ASIC2 subunits target acid-sensing ion channels to the synapse via an association with PSD-95

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

ligand-gated sodium channel activity

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

integral component of membrane

cell component

3 references

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

integral component of plasma membrane

ISO

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

negative regulation of neurotransmitter secretion

biological process

1 reference

14 February 2019

Presynaptic release probability is increased in hippocampal neurons from ASIC1 knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

1 reference

14 February 2019

The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

sodium ion transmembrane transport

3 references

2 references

regulation of membrane potential

1 reference

14 February 2019

Characterization of acid-sensing ion channels in medium spiny neurons of mouse striatum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

1 reference

14 February 2019

The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

protein homotrimerization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

calcium ion transmembrane transport

ISS

cellular response to pH

3 references

1 reference

14 February 2019

Characterization of acid-sensing ion channels in medium spiny neurons of mouse striatum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

calcium ion transport

1 reference

14 February 2019

The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory

response to acidic pH

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

14 February 2019

Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

14 February 2019

Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

Genetic mapping of ASIC4 and contrasting phenotype to ASIC1a in modulating innate fear and anxiety.

IDA

behavioral fear response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

Genetic mapping of ASIC4 and contrasting phenotype to ASIC1a in modulating innate fear and anxiety.

response to amphetamine

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

ion transmembrane transport

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

14 February 2019

Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

14 February 2019

Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

14 February 2019

Characterization of acid-sensing ion channels in medium spiny neurons of mouse striatum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

14 February 2019

Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NXK8

Epithelial sodium channel, conserved site

IDA

has part(s)

1 reference

stated in

InterPro Release 71.0