(Q21499225)

http://www.ebi.ac.uk/interpro/protein/O09161

Calsequestrin

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O09161

Calsequestrin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O09161&geneProductId=UniProtKB:O09161

24 April 2018

Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?protein=O09161&geneProductId=UniProtKB:O09161

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O09161&geneProductId=UniProtKB:O09161

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O09161&geneProductId=UniProtKB:O09161

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

protein kinase C binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

protein homodimerization activity

ISO

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

junctional membrane complex

cell component

1 reference

8 April 2019

The calsequestrin mutation CASQ2D307H does not affect protein stability and targeting to the junctional sarcoplasmic reticulum but compromises its dynamic regulation of calcium buffering

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

sarcoplasmic reticulum lumen

Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle

sarcoplasmic reticulum

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

intracellular anatomical structure

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O09161&geneProductId=UniProtKB:O09161

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

sarcoplasmic reticulum lumen

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

The calsequestrin mutation CASQ2D307H does not affect protein stability and targeting to the junctional sarcoplasmic reticulum but compromises its dynamic regulation of calcium buffering

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

regulation of muscle contraction

biological process

1 reference

8 April 2019

Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

TAS

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

14 February 2019

Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

14 February 2019

Regulation of Ca2+ signaling in transgenic mouse cardiac myocytes overexpressing calsequestrin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

regulation of heart rate

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

negative regulation of potassium ion transmembrane transporter activity

1 reference

8 April 2019

Modulation of human ether a gogo related channels by CASQ2 contributes to etiology of catecholaminergic polymorphic ventricular tachycardia (CPVT)

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

negative regulation of potassium ion transport

1 reference

8 April 2019

Modulation of human ether a gogo related channels by CASQ2 contributes to etiology of catecholaminergic polymorphic ventricular tachycardia (CPVT)

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

regulation of membrane repolarization

1 reference

8 April 2019

Modulation of human ether a gogo related channels by CASQ2 contributes to etiology of catecholaminergic polymorphic ventricular tachycardia (CPVT)

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

1 reference

8 April 2019

Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

The calsequestrin mutation CASQ2D307H does not affect protein stability and targeting to the junctional sarcoplasmic reticulum but compromises its dynamic regulation of calcium buffering

IMP

sarcomere organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

regulation of cardiac muscle cell contraction

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion

ISO

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

Regulation of Ca2+ signaling in transgenic mouse cardiac myocytes overexpressing calsequestrin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09161

Calsequestrin, conserved site

has part(s)

1 reference

stated in

InterPro Release 71.0