(Q21756777)

English

2-isopropylmalate synthase activity

Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+).

  • GO:0003852
  • alpha-IPM synthetase activity
  • isopropylmalate synthetase activity
  • isopropylmalate synthase activity
  • alpha-isopropylmalate synthetase activity
  • alpha-isopropylmalic synthetase activity
  • 3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating) activity
  • alpha-isopropylmalate synthase activity
  • acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)

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