(Q21979992)

Kelch-type beta propeller

1 reference

Kelch-like ECH-associated protein 1

1 reference

BTB/POZ domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

BTB/Kelch-associated domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Kelch repeat type 1, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

transcription factor binding

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

ubiquitin-protein transferase activity

IBA

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2X8&geneProductId=UniProtKB:Q9Z2X8

5 references

14 February 2019

Reversible memory loss in a mouse transgenic model of Alzheimer's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

Dihydro-CDDO-trifluoroethyl amide suppresses inflammatory responses in macrophages via activation of Nrf2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

Kinetic, Thermodynamic, and Structural Characterizations of the Association between Nrf2-DLGex Degron and Keap1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

protein homodimerization activity

IPI

1 reference

14 February 2019

Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

disordered domain specific binding

IMP

1 reference

14 February 2019

Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

identical protein binding

IPI

1 reference

14 February 2019

Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

Cul3-RING ubiquitin ligase complex

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2X8&geneProductId=UniProtKB:Q9Z2X8

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2X8&geneProductId=UniProtKB:Q9Z2X8

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2X8&geneProductId=UniProtKB:Q9Z2X8

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2X8&geneProductId=UniProtKB:Q9Z2X8

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2X8&geneProductId=UniProtKB:Q9Z2X8

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

endoplasmic reticulum

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

1 reference

14 February 2019

Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

protein-containing complex

1 reference

14 February 2019

Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

Cul3-RING ubiquitin ligase complex

ISO

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

cellular response to interleukin-4

biological process

1 reference

14 February 2019

Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

regulation of epidermal cell differentiation

IDA

1 reference

14 February 2019

Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

in utero embryonic development

IMP

1 reference

14 February 2019

Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

proteasomal ubiquitin-independent protein catabolic process

IMP

3 references

negative regulation of DNA-binding transcription factor activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2X8&geneProductId=UniProtKB:Q9Z2X8

transcription, DNA-templated

IBA

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2X8&geneProductId=UniProtKB:Q9Z2X8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

protein ubiquitination

5 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

proteasome-mediated ubiquitin-dependent protein catabolic process

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2X8&geneProductId=UniProtKB:Q9Z2X8

negative regulation of gene expression

IBA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

protein complex oligomerization

ISO

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

regulation of transcription, DNA-templated

ISO

1 reference

14 February 2019

Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2X8

1 reference

BTB/Kelch-associated

1 reference

BTB/POZ domain

1 reference

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016