(Q21980210)

Transcription factor, T-box

1 reference

T-box superfamily

1 reference

Transcription factor, T-box, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

31 January 2018

1 reference

31 January 2018

DNA-binding transcription factor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

14 February 2019

Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

5 references

14 February 2019

Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 regulates progenitor cell proliferation in the dental epithelium by modulating Pitx2 activation of p21

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Ash2l interacts with Tbx1 and is required during early embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Transcriptional control in cardiac progenitors: Tbx1 interacts with the BAF chromatin remodeling complex and regulates Wnt5a

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Interaction between Tbx1 and Hoxd10 and connection with TGFβ-BMP signal pathway during kidney development

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding

IPI

1 reference

14 February 2019

Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

2 references

6 references

14 February 2019

Isolation and characterization of a gene from the DiGeorge chromosomal region homologous to the mouse Tbx1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Properties of branchiomeric and somite-derived muscle development in Tbx1 mutant embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

The 22q11 deletion syndrome candidate gene Tbx1 determines thyroid size and positioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

pattern specification process

biological process

3 references

14 February 2019

The del22q11.2 candidate gene Tbx1 regulates branchiomeric myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 is required for proper neural crest migration and to stabilize spatial patterns during middle and inner ear development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Dose-dependent interaction of Tbx1 and Crkl and locally aberrant RA signaling in a model of del22q11 syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

negative regulation of mesenchymal cell apoptotic process

1 reference

14 February 2019

Cooperative function of Tbx1 and Brn4 in the periotic mesenchyme is necessary for cochlea formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

cellular response to retinoic acid

1 reference

14 February 2019

Retinoic acid down-regulates Tbx1 expression and induces abnormal differentiation of tongue muscles in fetal mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

positive regulation of protein phosphorylation

IEP

1 reference

14 February 2019

Partial rescue of the Tbx1 mutant heart phenotype by Fgf8: genetic evidence of impaired tissue response to Fgf8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

semicircular canal morphogenesis

1 reference

14 February 2019

Great vessel development requires biallelic expression of Chd7 and Tbx1 in pharyngeal ectoderm in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

blood vessel morphogenesis

1 reference

14 February 2019

TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

muscle organ morphogenesis

1 reference

14 February 2019

Distinct regulatory cascades govern extraocular and pharyngeal arch muscle progenitor cell fates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

1 reference

14 February 2019

Retinoic acid down-regulates Tbx1 expression and induces abnormal differentiation of tongue muscles in fetal mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

positive regulation of tongue muscle cell differentiation

1 reference

14 February 2019

Retinoic acid down-regulates Tbx1 expression and induces abnormal differentiation of tongue muscles in fetal mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

positive regulation of epithelial cell proliferation

5 references

14 February 2019

Cooperative function of Tbx1 and Brn4 in the periotic mesenchyme is necessary for cochlea formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

In vivo genetic ablation of the periotic mesoderm affects cell proliferation survival and differentiation in the cochlea

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Enamel-free teeth: Tbx1 deletion affects amelogenesis in rodent incisors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 regulates progenitor cell proliferation in the dental epithelium by modulating Pitx2 activation of p21

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 regulates population, proliferation and cell fate determination of otic epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

3 references

14 February 2019

Isolation and characterization of a gene from the DiGeorge chromosomal region homologous to the mouse Tbx1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

In vivo response to high-resolution variation of Tbx1 mRNA dosage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

mesenchymal cell apoptotic process

1 reference

14 February 2019

Cooperative function of Tbx1 and Brn4 in the periotic mesenchyme is necessary for cochlea formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Tbx1 regulates progenitor cell proliferation in the dental epithelium by modulating Pitx2 activation of p21

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

negative regulation of cell differentiation

1 reference

14 February 2019

Tbx1 regulates proliferation and differentiation of multipotent heart progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

muscle cell fate commitment

1 reference

14 February 2019

Properties of branchiomeric and somite-derived muscle development in Tbx1 mutant embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

The del22q11.2 candidate gene Tbx1 regulates branchiomeric myogenesis

muscle organ development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

4 references

14 February 2019

Mesodermal expression of Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Fgf8 expression in the Tbx1 domain causes skeletal abnormalities and modifies the aortic arch but not the outflow tract phenotype of Tbx1 mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Full spectrum of malformations in velo-cardio-facial syndrome/DiGeorge syndrome mouse models by altering Tbx1 dosage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

outflow tract morphogenesis

3 references

14 February 2019

In vivo response to high-resolution variation of Tbx1 mRNA dosage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

The del22q11.2 candidate gene Tbx1 controls regional outflow tract identity and coronary artery patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

A Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

vagus nerve morphogenesis

1 reference

14 February 2019

Absence of the vagus nerve in the stomach of Tbx1-/- mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

otic vesicle morphogenesis

1 reference

14 February 2019

Tbx1 regulates population, proliferation and cell fate determination of otic epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

Tissue-specific roles of Tbx1 in the development of the outer, middle and inner ear, defective in 22q11DS patients

outer ear morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

negative regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Hes1 expression is reduced in Tbx1 null cells and is required for the development of structures affected in 22q11 deletion syndrome

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

cellular response to fibroblast growth factor stimulus

1 reference

14 February 2019

Partial rescue of the Tbx1 mutant heart phenotype by Fgf8: genetic evidence of impaired tissue response to Fgf8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

Tbx1 regulates Vegfr3 and is required for lymphatic vessel development

lymph vessel development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

transcription, DNA-templated

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70323&geneProductId=UniProtKB:P70323

outflow tract septum morphogenesis

1 reference

14 February 2019

Partial rescue of the Tbx1 mutant heart phenotype by Fgf8: genetic evidence of impaired tissue response to Fgf8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

1 reference

14 February 2019

Full spectrum of malformations in velo-cardio-facial syndrome/DiGeorge syndrome mouse models by altering Tbx1 dosage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

9 references

14 February 2019

Isolation and characterization of a gene from the DiGeorge chromosomal region homologous to the mouse Tbx1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Dose-dependent interaction of Tbx1 and Crkl and locally aberrant RA signaling in a model of del22q11 syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

Dissection of Tbx1 and Fgf interactions in mouse models of 22q11DS suggests functional redundancy

blood vessel remodeling

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

thyroid gland development

4 references

14 February 2019

Full spectrum of malformations in velo-cardio-facial syndrome/DiGeorge syndrome mouse models by altering Tbx1 dosage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Early thyroid development requires a Tbx1-Fgf8 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

The 22q11 deletion syndrome candidate gene Tbx1 determines thyroid size and positioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Early thyroid development requires a Tbx1-Fgf8 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

determination of left/right symmetry

1 reference

14 February 2019

Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

retinoic acid receptor signaling pathway

1 reference

14 February 2019

Retinoic acid down-regulates Tbx1 expression and induces abnormal differentiation of tongue muscles in fetal mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice

blood vessel development

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 expression in pharyngeal epithelia is necessary for pharyngeal arch artery development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Dose-dependent interaction of Tbx1 and Crkl and locally aberrant RA signaling in a model of del22q11 syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

positive regulation of mesenchymal cell proliferation

1 reference

14 February 2019

Cooperative function of Tbx1 and Brn4 in the periotic mesenchyme is necessary for cochlea formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

Tissue-specific roles of Tbx1 in the development of the outer, middle and inner ear, defective in 22q11DS patients

inner ear morphogenesis

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

TBX1 is required for inner ear morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Suppression of neural fate and control of inner ear morphogenesis by Tbx1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 is required for proper neural crest migration and to stabilize spatial patterns during middle and inner ear development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

muscle tissue morphogenesis

1 reference

14 February 2019

Distinct regulatory cascades govern extraocular and pharyngeal arch muscle progenitor cell fates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways

cochlea morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

positive regulation of cell population proliferation

1 reference

14 February 2019

Timed mutation and cell-fate mapping reveal reiterated roles of Tbx1 during embryogenesis, and a crucial function during segmentation of the pharyngeal system via regulation of endoderm expansion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

4 references

14 February 2019

DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Great vessel development requires biallelic expression of Chd7 and Tbx1 in pharyngeal ectoderm in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectoderm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Prdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

Tissue-specific roles of Tbx1 in the development of the outer, middle and inner ear, defective in 22q11DS patients

middle ear morphogenesis

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Mesodermal Tbx1 is required for patterning the proximal mandible in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 is required for proper neural crest migration and to stabilize spatial patterns during middle and inner ear development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

branching involved in blood vessel morphogenesis

1 reference

14 February 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

1 reference

14 February 2019

Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

embryonic cranial skeleton morphogenesis

1 reference

14 February 2019

Full spectrum of malformations in velo-cardio-facial syndrome/DiGeorge syndrome mouse models by altering Tbx1 dosage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

positive regulation of secondary heart field cardioblast proliferation

1 reference

14 February 2019

Tbx1 regulates proliferation and differentiation of multipotent heart progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

Enamel-free teeth: Tbx1 deletion affects amelogenesis in rodent incisors

enamel mineralization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

1 reference

14 February 2019

DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

cell population proliferation

1 reference

14 February 2019

Mesodermal expression of Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

1 reference

14 February 2019

Mesodermal Tbx1 is required for patterning the proximal mandible in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

positive regulation of MAPK cascade

1 reference

14 February 2019

Partial rescue of the Tbx1 mutant heart phenotype by Fgf8: genetic evidence of impaired tissue response to Fgf8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

positive regulation of transcription by RNA polymerase II

5 references

14 February 2019

Hes1 expression is reduced in Tbx1 null cells and is required for the development of structures affected in 22q11 deletion syndrome

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Ash2l interacts with Tbx1 and is required during early embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

pharyngeal system development

5 references

14 February 2019

Isolation and characterization of a gene from the DiGeorge chromosomal region homologous to the mouse Tbx1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Timed mutation and cell-fate mapping reveal reiterated roles of Tbx1 during embryogenesis, and a crucial function during segmentation of the pharyngeal system via regulation of endoderm expansion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

A Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

regulation of animal organ morphogenesis

3 references

14 February 2019

Early thyroid development requires a Tbx1-Fgf8 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

The 22q11 deletion syndrome candidate gene Tbx1 determines thyroid size and positioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Early thyroid development requires a Tbx1-Fgf8 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

transcription by RNA polymerase II

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70323&geneProductId=UniProtKB:P70323

positive regulation of transcription, DNA-templated

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Identification of a novel nuclear localization signal in Tbx1 that is deleted in DiGeorge syndrome patients harboring the 1223delC mutation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

14 February 2019

Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70323

Transcription factor, T-box, conserved site

has part(s)

1 reference