(Q21980217)

English

T-box18

mammalian protein found in Mus musculus

T-box protein 18
Tbx18
T-box transcription factor TBX18

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

p53-like transcription factor, DNA-binding

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9EPZ6

Transcription factor, T-box

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9EPZ6

T-box superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9EPZ6

Transcription factor, T-box, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

protein homodimerization activity

determination method

1 reference

14 February 2019

Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

DNA-binding transcription factor activity

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

transcription cis-regulatory region binding

determination method

1 reference

14 February 2019

Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

1 reference

14 February 2019

Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method

3 references

11 October 2018

Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPZ6&geneProductId=UniProtKB:Q9EPZ6

determination method

14 February 2019

Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

14 February 2019

Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

protein binding

determination method

1 reference

14 February 2019

SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

protein heterodimerization activity

determination method

1 reference

14 February 2019

Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

Tle3-Aes complex

determination method

1 reference

14 February 2019

Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

14 February 2019

Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

biological process

determination method

1 reference

14 February 2019

The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

renal system development

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

cell differentiation

determination method

1 reference

14 February 2019

Deafness in mice lacking the T-box transcription factor Tbx18 in otic fibrocytes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

ureter development

determination method

1 reference

14 February 2019

Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

regulation of transcription, DNA-templated

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

positive regulation of cell-cell adhesion

determination method

1 reference

14 February 2019

Deafness in mice lacking the T-box transcription factor Tbx18 in otic fibrocytes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

positive regulation of epithelial cell proliferation

determination method

1 reference

14 February 2019

Tbx18 regulates the development of the ureteral mesenchyme

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

anatomical structure formation involved in morphogenesis

determination method

1 reference

14 February 2019

Formation of the sinus node head and differentiation of sinus node myocardium are independently regulated by Tbx18 and Tbx3

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

negative regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

sensory perception of sound

determination method

1 reference

14 February 2019

Deafness in mice lacking the T-box transcription factor Tbx18 in otic fibrocytes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

smooth muscle cell differentiation

determination method

1 reference

14 February 2019

Tbx18 regulates the development of the ureteral mesenchyme

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

transcription, DNA-templated

determination method

1 reference

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPZ6&geneProductId=UniProtKB:Q9EPZ6

determination method

sinoatrial node development

determination method

1 reference

14 February 2019

Formation of the sinus node head and differentiation of sinus node myocardium are independently regulated by Tbx18 and Tbx3

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

multicellular organism development

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation

determination method

1 reference

14 February 2019

Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

positive regulation of mesenchymal cell proliferation

determination method

1 reference

14 February 2019

Tbx18 regulates the development of the ureteral mesenchyme

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

cochlea morphogenesis

determination method

1 reference

14 February 2019

Deafness in mice lacking the T-box transcription factor Tbx18 in otic fibrocytes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

positive regulation of mesenchymal cell proliferation involved in ureter development

determination method

1 reference

14 February 2019

SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

morphogenesis of embryonic epithelium

determination method

1 reference

14 February 2019

Tbx18 regulates the development of the ureteral mesenchyme

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

anterior/posterior axis specification

determination method

1 reference

14 February 2019

The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPZ6

determination method

Transcription factor, T-box, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9EPZ6

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000034991

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000034991

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