(Q21980218)

English

T-box 20

mammalian protein found in Mus musculus

Tbx20
T-box transcription factor TBX20
T-box protein 20

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

p53-like transcription factor, DNA-binding

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ES03

Transcription factor, T-box

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ES03

T-box superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ES03

Transcription factor, T-box, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

determination method

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

Differential expression and function of Tbx5 and Tbx20 in cardiac development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

transcription coactivator activity

determination method

6 references

27 March 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES03&geneProductId=UniProtKB:Q9ES03

determination method

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES03&geneProductId=UniProtKB:Q9ES03

determination method

27 March 2018

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES03&geneProductId=UniProtKB:Q9ES03

determination method

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES03&geneProductId=UniProtKB:Q9ES03

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES03&geneProductId=UniProtKB:Q9ES03

determination method

21 June 2018

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES03&geneProductId=UniProtKB:Q9ES03

determination method

RNA polymerase II transcription regulatory region sequence-specific DNA binding

determination method

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

DNA-binding transcription factor activity

determination method

4 references

14 February 2019

Cloning and expression analysis of the mouse T-box gene tbx20

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

Differential expression and function of Tbx5 and Tbx20 in cardiac development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

DNA-binding transcription activator activity, RNA polymerase II-specific

determination method

2 references

11 October 2018

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES03&geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

1 reference

14 February 2019

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

transcription coactivator activity

determination method

1 reference

11 October 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES03&geneProductId=UniProtKB:Q9ES03

determination method

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

determination method

1 reference

14 February 2019

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

determination method

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

biological process

cardiac septum development

determination method

1 reference

14 February 2019

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

muscle contraction

determination method

1 reference

14 February 2019

Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

regulation of transcription, DNA-templated

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

negative regulation of SMAD protein complex assembly

determination method

1 reference

14 February 2019

Tbx20 interacts with smads to confine tbx2 expression to the atrioventricular canal

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

regulation of epithelial to mesenchymal transition

determination method

1 reference

14 February 2019

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

outflow tract morphogenesis

determination method

1 reference

14 February 2019

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

cardiac muscle tissue morphogenesis

determination method

1 reference

14 February 2019

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

neuron migration

determination method

1 reference

14 February 2019

T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

blood circulation

determination method

1 reference

14 February 2019

Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

transcription, DNA-templated

determination method

1 reference

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES03&geneProductId=UniProtKB:Q9ES03

determination method

pulmonary valve formation

determination method

1 reference

14 February 2019

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

embryonic heart tube development

determination method

2 references

14 February 2019

Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

outflow tract septum morphogenesis

determination method

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

endocardial cushion morphogenesis

determination method

1 reference

14 February 2019

Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

determination method

3 references

14 February 2019

Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

endocardial cushion formation

determination method

1 reference

14 February 2019

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

multicellular organism development

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

positive regulation of transcription, DNA-templated

determination method

positive regulation of cardiac muscle cell proliferation

determination method

1 reference

14 February 2019

Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

visceral motor neuron differentiation

determination method

1 reference

14 February 2019

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

embryonic heart tube morphogenesis

determination method

1 reference

14 February 2019

Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

aortic valve development

determination method

1 reference

14 February 2019

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

pericardium morphogenesis

determination method

1 reference

14 February 2019

Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

branching involved in blood vessel morphogenesis

determination method

1 reference

14 February 2019

Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

cell population proliferation

determination method

1 reference

14 February 2019

T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

negative regulation of transcription, DNA-templated

determination method

3 references

14 February 2019

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

Differential expression and function of Tbx5 and Tbx20 in cardiac development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

14 February 2019

T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

dorsal/ventral pattern formation

determination method

1 reference

14 February 2019

Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

cardiac right ventricle morphogenesis

determination method

1 reference

14 February 2019

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

tricuspid valve development

determination method

1 reference

14 February 2019

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

positive regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

embryonic heart tube elongation

determination method

1 reference

14 February 2019

Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ES03

determination method

transcription by RNA polymerase II

determination method

1 reference

21 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES03&geneProductId=UniProtKB:Q9ES03

determination method

Transcription factor, T-box, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ES03

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000052591

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000052591

ENSMUSP00000126318

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000126318

ENSMUSP00000149186

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000149186

Sitelinks

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Multilingual sites(0 entries)

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