(Q21981009)

English

CD247 antigen

mammalian protein found in Mus musculus

Cd247
T-cell receptor T3 eta chain
T-cell receptor T3 zeta chain
CD3 antigen, zeta polypeptide
CD3-zeta/eta
T-cell surface glycoprotein CD3 zeta chain

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Statements

1 reference

25 May 2022

T-cell surface glycoprotein CD3 zeta subunit

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P24161

membrane proteins

1 reference

based on heuristic

inferred from GOA cell component → membrane

Phosphorylated immunoreceptor signalling ITAM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

5 references

9 May 2019

Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

9 May 2019

The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

9 May 2019

Lck availability during thymic selection determines the recognition specificity of the T cell repertoire

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

9 May 2019

The protein tyrosine phosphatase PTPN4/PTP-MEG1, an enzyme capable of dephosphorylating the TCR ITAMs and regulating NF-kappaB, is dispensable for T cell development and/or T cell effector functions

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

9 May 2019

Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method

IPI

transmembrane signaling receptor activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method

IEA

cell component

integral component of membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method

IEA

alpha-beta T cell receptor complex

determination method

IDA

T cell receptor complex

3 references

alpha-beta T cell receptor complex

3 references

9 May 2019

A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

9 May 2019

Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method

IBA

biological process

T cell receptor signaling pathway

1 reference

24 April 2018

Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24161&geneProductId=UniProtKB:P24161

determination method

IDA

adaptive immune response

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method

IEA

immune system process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method

IEA

interleukin-2 production

1 reference

9 May 2019

Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR).

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method

IGI

positive regulation of protein localization to cell surface

1 reference

9 May 2019

Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR).

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method

IDA

has part(s)

Phosphorylated immunoreceptor signalling ITAM

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P24161

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

(Q21981009)

CD247 antigen

Statements

Identifiers

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