(Q21981126)

glutathione peroxidase

1 reference

Glutathione peroxidase active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Glutathione peroxidase conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

SelT, SelW, SelH, and Rdx12: genomics and molecular insights into the functions of selenoproteins of a novel thioredoxin-like family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

IPI

oxidoreductase activity

1 reference

14 February 2019

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

glutathione peroxidase activity

19 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Low glutathione peroxidase activity in Gpx1 knockout mice protects jejunum crypts from gamma-irradiation damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Cellular glutathione peroxidase deficiency and endothelial dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Knockout of cellular glutathione peroxidase gene renders mice susceptible to diquat-induced oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

The effect of aging on glutathione peroxidase-i knockout mice-resistance of the lens to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Effects of dietary iron overload on glutathione peroxidase knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Mice with combined disruption of Gpx1 and Gpx2 genes have colitis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Glutathione peroxidase knockout mice are susceptible to myocardial ischemia reperfusion injury

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Targeted mutation of the gene for cellular glutathione peroxidase (Gpx1) increases noise-induced hearing loss in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Microflora trigger colitis in mice deficient in selenium-dependent glutathione peroxidase and induce Gpx2 gene expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

The nature of antioxidant defense mechanisms: a lesson from transgenic studies

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Developmental changes in murine brain antioxidant enzymes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Redox imbalance and mutagenesis in spleens of mice harboring a hypomorphic allele of Gpdx(a) encoding glucose 6-phosphate dehydrogenase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

glutathione peroxidase activity

IDA

20 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

The effect of aging on glutathione peroxidase-i knockout mice-resistance of the lens to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

The nature of antioxidant defense mechanisms: a lesson from transgenic studies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Targeted mutation of the gene for cellular glutathione peroxidase (Gpx1) increases noise-induced hearing loss in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Glutathione peroxidase knockout mice are susceptible to myocardial ischemia reperfusion injury

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Effects of dietary iron overload on glutathione peroxidase knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Low glutathione peroxidase activity in Gpx1 knockout mice protects jejunum crypts from gamma-irradiation damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Knockout of cellular glutathione peroxidase gene renders mice susceptible to diquat-induced oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Cellular glutathione peroxidase deficiency and endothelial dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Microflora trigger colitis in mice deficient in selenium-dependent glutathione peroxidase and induce Gpx2 gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Mice with combined disruption of Gpx1 and Gpx2 genes have colitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Developmental changes in murine brain antioxidant enzymes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Redox imbalance and mutagenesis in spleens of mice harboring a hypomorphic allele of Gpdx(a) encoding glucose 6-phosphate dehydrogenase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

4 references

14 February 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

6 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

31 January 2018

Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

31 January 2018

The Gpx1 gene encodes mitochondrial glutathione peroxidase in the mouse liver

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

31 January 2018

A mitochondrial protein compendium elucidates complex I disease biology

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

31 January 2018

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

6 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

The Gpx1 gene encodes mitochondrial glutathione peroxidase in the mouse liver

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

A mitochondrial protein compendium elucidates complex I disease biology

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

The Gpx1 gene encodes mitochondrial glutathione peroxidase in the mouse liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

A mitochondrial protein compendium elucidates complex I disease biology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

3 references

1 reference

14 February 2019

Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

1 reference

14 February 2019

Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

response to hydroperoxide

1 reference

14 February 2019

Retinal light damage: structural and functional effects of the antioxidant glutathione peroxidase-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

1 reference

14 February 2019

Targeted mutation of the gene for cellular glutathione peroxidase (Gpx1) increases noise-induced hearing loss in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

angiogenesis involved in wound healing

1 reference

14 February 2019

Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

positive regulation of protein kinase B signaling

1 reference

14 February 2019

Diminished Akt phosphorylation in neurons lacking glutathione peroxidase-1 (Gpx1) leads to increased susceptibility to oxidative stress-induced cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

Glutathione-peroxidase-1 null muscle progenitor cells are globally defective

fat cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

response to symbiotic bacterium

1 reference

14 February 2019

Microflora trigger colitis in mice deficient in selenium-dependent glutathione peroxidase and induce Gpx2 gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

blood vessel endothelial cell migration

1 reference

14 February 2019

Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

skeletal muscle tissue regeneration

1 reference

14 February 2019

Glutathione-peroxidase-1 null muscle progenitor cells are globally defective

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

regulation of neuron apoptotic process

1 reference

14 February 2019

Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

Mice with combined disruption of Gpx1 and Gpx2 genes have colitis

temperature homeostasis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

1 reference

14 February 2019

Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

cell population proliferation

1 reference

14 February 2019

Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

response to reactive oxygen species

5 references

14 February 2019

Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Opposite roles of selenium-dependent glutathione peroxidase-1 in superoxide generator diquat- and peroxynitrite-induced apoptosis and signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Genetic modification of the manganese superoxide dismutase/glutathione peroxidase 1 pathway influences intracellular ROS generation in quiescent, but not contracting, skeletal muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Glutathione-peroxidase-1 null muscle progenitor cells are globally defective

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

negative regulation of inflammatory response to antigenic stimulus

1 reference

14 February 2019

Microflora trigger colitis in mice deficient in selenium-dependent glutathione peroxidase and induce Gpx2 gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

triglyceride metabolic process

1 reference

14 February 2019

Effects of dietary iron overload on glutathione peroxidase knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

response to toxic substance

1 reference

14 February 2019

Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

response to gamma radiation

1 reference

14 February 2019

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

negative regulation of apoptotic process

1 reference

14 February 2019

Dramatic extension of tumor latency and correction of neurobehavioral phenotype in Atm-mutant mice with a nitroxide antioxidant

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

skeletal muscle fiber development

1 reference

14 February 2019

Glutathione-peroxidase-1 null muscle progenitor cells are globally defective

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

endothelial cell development

1 reference

14 February 2019

Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

response to oxidative stress

9 references

14 February 2019

Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Heterozygous cellular glutathione peroxidase deficiency in the mouse: abnormalities in vascular and cardiac function and structure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Selenium-dependent cellular glutathione peroxidase protects mice against a pro-oxidant-induced oxidation of NADPH, NADH, lipids, and protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Glutathione-peroxidase-1 null muscle progenitor cells are globally defective

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Cellular glutathione peroxidase deficiency and endothelial dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

1 reference

14 February 2019

Glutathione-peroxidase-1 null muscle progenitor cells are globally defective

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

intrinsic apoptotic signaling pathway in response to oxidative stress

2 references

14 February 2019

Diminished Akt phosphorylation in neurons lacking glutathione peroxidase-1 (Gpx1) leads to increased susceptibility to oxidative stress-induced cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Opposite roles of selenium-dependent glutathione peroxidase-1 in superoxide generator diquat- and peroxynitrite-induced apoptosis and signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

biological process involved in interaction with symbiont

1 reference

14 February 2019

Microflora trigger colitis in mice deficient in selenium-dependent glutathione peroxidase and induce Gpx2 gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

1 reference

14 February 2019

Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

hydrogen peroxide catabolic process

8 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Targeted mutation of the gene for cellular glutathione peroxidase (Gpx1) increases noise-induced hearing loss in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

The nature of antioxidant defense mechanisms: a lesson from transgenic studies

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Heterozygous cellular glutathione peroxidase deficiency in the mouse: abnormalities in vascular and cardiac function and structure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

response to hydrogen peroxide

5 references

1 January 2018

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352

cellular oxidant detoxification

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

cellular response to glucose stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

glutathione metabolic process

ISO

3 references

response to selenium ion

3 references

response to hydrogen peroxide

6 references

14 February 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

hydrogen peroxide catabolic process

IBA

9 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

The nature of antioxidant defense mechanisms: a lesson from transgenic studies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Targeted mutation of the gene for cellular glutathione peroxidase (Gpx1) increases noise-induced hearing loss in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352

Glutathione peroxidase active site

IBA

has part(s)

1 reference

Glutathione peroxidase conserved site

1 reference