Wikidata

(Q21981223)

English

Protein phosphatase 1 catalytic subunit alpha

mammalian protein found in Mus musculus

  • protein phosphatase 1, catalytic subunit, alpha isoform
  • serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  • Ppp1ca
  • PP-1A
In more languages

Statements

molecular function
protein binding
determination method
IPI
11 references
retrieved
14 February 2019
stated in
KCTD20, a relative of BTBD10, is a positive regulator of Akt
GOA
curator
UniProt
UniProt protein ID
P62137
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IPI
retrieved
14 February 2019
stated in
A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB
GOA
curator
UniProt
UniProt protein ID
P62137
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IPI
retrieved
14 February 2019
stated in
SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IPI
retrieved
14 February 2019
stated in
Fasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation of hepatic glycogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IPI
retrieved
14 February 2019
stated in
The anti-apoptotic molecules Bcl-xL and Bcl-w target protein phosphatase 1alpha to Bad
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IPI
retrieved
14 February 2019
stated in
delta-Protocadherins: a gene family expressed differentially in the mouse brain
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IPI
retrieved
14 February 2019
stated in
PKC-alpha regulates cardiac contractility and propensity toward heart failure
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IPI
retrieved
14 February 2019
stated in
Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IPI
retrieved
14 February 2019
stated in
Dab2 stabilizes Axin and attenuates Wnt/beta-catenin signaling by preventing protein phosphatase 1 (PP1)-Axin interactions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IPI
retrieved
14 February 2019
stated in
A limited screen for protein interactions reveals new roles for protein phosphatase 1 in cell cycle control and apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IPI
retrieved
14 February 2019
stated in
Alterations in the interactome of serine/threonine protein phosphatase type-1 in atrial fibrillation patients.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IPI
protein serine/threonine phosphatase activity
determination method
IDA
IEA
ISS
TAS
6 references
retrieved
10 September 2018
stated in
Chromosomal localization of human, rat, and mouse protein phosphatase type 1 beta catalytic subunit genes (PPP1CB) by fluorescence in situ hybridization
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62137&geneProductId=UniProtKB:P62137
determination method
TAS
retrieved
10 September 2018
stated in
Characterization of protein phosphatases in mouse oocytes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62137&geneProductId=UniProtKB:P62137
determination method
TAS
retrieved
10 September 2018
stated in
Comparative mapping of the gene encoding the catalytic subunit of protein phosphatase type 1 alpha (PPP1CA) to human, rat, and mouse chromosomes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62137&geneProductId=UniProtKB:P62137
determination method
ISS
retrieved
10 September 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62137&geneProductId=UniProtKB:P62137
determination method
IEA
retrieved
10 September 2018
stated in
The anti-apoptotic molecules Bcl-xL and Bcl-w target protein phosphatase 1alpha to Bad
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62137&geneProductId=UniProtKB:P62137
determination method
IDA
retrieved
10 September 2018
stated in
SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62137&geneProductId=UniProtKB:P62137
determination method
IDA
protein serine/threonine phosphatase activity
determination method
IBA
IDA
IEA
ISS
TAS
7 references
retrieved
14 February 2019
stated in
Chromosomal localization of human, rat, and mouse protein phosphatase type 1 beta catalytic subunit genes (PPP1CB) by fluorescence in situ hybridization
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
TAS
retrieved
14 February 2019
stated in
Characterization of protein phosphatases in mouse oocytes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
TAS
retrieved
14 February 2019
stated in
Comparative mapping of the gene encoding the catalytic subunit of protein phosphatase type 1 alpha (PPP1CA) to human, rat, and mouse chromosomes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IEA
retrieved
14 February 2019
stated in
The anti-apoptotic molecules Bcl-xL and Bcl-w target protein phosphatase 1alpha to Bad
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IDA
retrieved
14 February 2019
stated in
SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IBA
cell component
cytoplasm
determination method
IDA
IEA
ISO
6 references
retrieved
10 September 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62137&geneProductId=UniProtKB:P62137
determination method
ISO
retrieved
10 September 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P62137
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62137&geneProductId=UniProtKB:P62137
determination method
IEA
retrieved
10 September 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62137&geneProductId=UniProtKB:P62137
determination method
IEA
retrieved
10 September 2018
stated in
Characterization of protein phosphatases in mouse oocytes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62137&geneProductId=UniProtKB:P62137
determination method
IDA
retrieved
10 September 2018
stated in
Fasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation of hepatic glycogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62137&geneProductId=UniProtKB:P62137
determination method
IDA
retrieved
10 September 2018
stated in
Protein phosphatase 1alpha is required for murine lung growth and morphogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P62137&geneProductId=UniProtKB:P62137
determination method
IDA
cytoplasm
determination method
IBA
IDA
IEA
ISO
7 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P62137
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IEA
retrieved
14 February 2019
stated in
Fasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation of hepatic glycogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IDA
retrieved
14 February 2019
stated in
Protein phosphatase 1alpha is required for murine lung growth and morphogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IDA
retrieved
14 February 2019
stated in
Characterization of protein phosphatases in mouse oocytes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IBA
biological process
protein dephosphorylation
determination method
IDA
TAS
IEA
ISO
7 references
retrieved
14 February 2019
stated in
Characterization of protein phosphatases in mouse oocytes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
TAS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IEA
retrieved
14 February 2019
stated in
The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1
GOA
curator
UniProt
UniProt protein ID
P62137
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IDA
retrieved
14 February 2019
stated in
The anti-apoptotic molecules Bcl-xL and Bcl-w target protein phosphatase 1alpha to Bad
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IDA
retrieved
14 February 2019
stated in
Merlin, the Product of the Nf2 Tumor Suppressor Gene, Is an Inhibitor of the p21-Activated Kinase, Pak1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IDA
retrieved
14 February 2019
stated in
SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62137
determination method
IDA

Identifiers

 
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