(Q21981309)

English

Cullin 3

mammalian protein found in Mus musculus

Cul3
cullin-3

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Winged helix DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9JLV5

Cullin homology domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9JLV5

Winged helix-like DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9JLV5

Cullin repeat-like-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9JLV5

Cullin, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Cullin homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Cullin protein, neddylation domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Cullin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein homodimerization activity

determination method

1 reference

14 February 2019

MUF1/leucine-rich repeat containing 41 (LRRC41), a substrate of RhoBTB-dependent cullin 3 ubiquitin ligase complexes, is a predominantly nuclear dimeric protein

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

ubiquitin-protein transferase activity

determination method

3 references

POZ domain binding

determination method

3 references

determination method

1 reference

14 February 2019

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

protein heterodimerization activity

determination method

1 reference

14 February 2019

MUF1/leucine-rich repeat containing 41 (LRRC41), a substrate of RhoBTB-dependent cullin 3 ubiquitin ligase complexes, is a predominantly nuclear dimeric protein

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

protein binding

determination method

3 references

14 February 2019

A negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

Kbtbd5 is regulated by MyoD and restricted to the myogenic lineage

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

ubiquitin protein ligase activity

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

polar microtubule

determination method

3 references

determination method

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

A negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

Cul3-RING ubiquitin ligase complex

determination method

3 references

determination method

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

A negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

sperm flagellum

determination method

3 references

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

cell projection

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

SCF ubiquitin ligase complex

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

biological process

mitotic cell cycle

determination method

1 reference

14 February 2019

Constitutive turnover of cyclin E by Cul3 maintains quiescence

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

positive regulation of mitotic metaphase/anaphase transition

determination method

3 references

regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

A negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

protein polyubiquitination

determination method

3 references

in utero embryonic development

determination method

1 reference

14 February 2019

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

stem cell division

determination method

1 reference

14 February 2019

Ubiquitin-dependent regulation of COPII coat size and function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

mitotic metaphase plate congression

determination method

3 references

COPII vesicle coating

determination method

3 references

vesicle-mediated transport

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

fibroblast apoptotic process

determination method

1 reference

14 February 2019

Constitutive turnover of cyclin E by Cul3 maintains quiescence

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

stress fiber assembly

determination method

3 references

cell morphogenesis

determination method

1 reference

14 February 2019

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

integrin-mediated signaling pathway

determination method

1 reference

14 February 2019

Ubiquitin-dependent regulation of COPII coat size and function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

cell projection organization

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

determination method

3 references

protein monoubiquitination

determination method

3 references

endoplasmic reticulum to Golgi vesicle-mediated transport

determination method

3 references

positive regulation of cytokinesis

determination method

3 references

proteasome-mediated ubiquitin-dependent protein catabolic process

determination method

4 references

10 September 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JLV5&geneProductId=UniProtKB:Q9JLV5

determination method

10 September 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JLV5&geneProductId=UniProtKB:Q9JLV5

determination method

10 September 2018

Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JLV5&geneProductId=UniProtKB:Q9JLV5

determination method

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JLV5&geneProductId=UniProtKB:Q9JLV5

determination method

determination method

1 reference

14 February 2019

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

liver morphogenesis

determination method

1 reference

14 February 2019

Constitutive turnover of cyclin E by Cul3 maintains quiescence

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

negative regulation of Rho protein signal transduction

determination method

3 references

negative regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

Constitutive turnover of cyclin E by Cul3 maintains quiescence

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

trophectodermal cellular morphogenesis

determination method

1 reference

14 February 2019

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

protein ubiquitination

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

Wnt signaling pathway

determination method

1 reference

14 February 2019

A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

embryonic cleavage

determination method

1 reference

14 February 2019

Ubiquitin-dependent regulation of COPII coat size and function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

nuclear protein quality control by the ubiquitin-proteasome system

determination method

3 references

ubiquitin-dependent protein catabolic process

determination method

4 references

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JLV5&geneProductId=UniProtKB:Q9JLV5

determination method

24 April 2018

KCTD10 is involved in the cardiovascular system and Notch signaling during early embryonic development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JLV5&geneProductId=UniProtKB:Q9JLV5

determination method

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JLV5&geneProductId=UniProtKB:Q9JLV5

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JLV5&geneProductId=UniProtKB:Q9JLV5

determination method

ubiquitin-dependent protein catabolic process

determination method

5 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

KCTD10 is involved in the cardiovascular system and Notch signaling during early embryonic development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

proteasome-mediated ubiquitin-dependent protein catabolic process

determination method

5 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JLV5

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000130738

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000130738

ENSMUSP00000126630

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000126630

ENSMUSP00000130010

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000130010

ENSMUSP00000131891

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000131891

ENSMUSP00000132485

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000132485

PDB structure ID

1 reference

UniProt protein ID

10 August 2016

language of work or name

Sitelinks

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Wiktionary(0 entries)

Multilingual sites(0 entries)

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