(Q21981310)

English

Cullin 1

mammalian protein found in Mus musculus

CUL-1
cullin-1
Cul1

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Winged helix DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9WTX6

Cullin homology domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9WTX6

Winged helix-like DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9WTX6

Cullin repeat-like-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9WTX6

Cullin, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Cullin homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Cullin protein, neddylation domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Cullin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein binding

determination method

4 references

14 February 2019

Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

Fbxw8 is essential for Cul1-Cul7 complex formation and for placental development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

NEDD8 links cullin-RING ubiquitin ligase function to the p97 pathway

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

ubiquitin-protein transferase activity

determination method

1 reference

14 January 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTX6&geneProductId=UniProtKB:Q9WTX6

determination method

cullin-RING ubiquitin ligase complex

determination method

SCF ubiquitin ligase complex

determination method

6 references

27 February 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTX6&geneProductId=UniProtKB:Q9WTX6

determination method

27 February 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTX6&geneProductId=UniProtKB:Q9WTX6

determination method

27 February 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTX6&geneProductId=UniProtKB:Q9WTX6

determination method

27 February 2018

FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTX6&geneProductId=UniProtKB:Q9WTX6

determination method

27 February 2018

E3 ubiquitin ligase that recognizes sugar chains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTX6&geneProductId=UniProtKB:Q9WTX6

determination method

27 February 2018

Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTX6&geneProductId=UniProtKB:Q9WTX6

determination method

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

SCF ubiquitin ligase complex

determination method

7 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

E3 ubiquitin ligase that recognizes sugar chains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

cullin-RING ubiquitin ligase complex

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

biological process

animal organ morphogenesis

determination method

1 reference

14 February 2019

Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

determination method

3 references

10 September 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTX6&geneProductId=UniProtKB:Q9WTX6

determination method

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTX6&geneProductId=UniProtKB:Q9WTX6

determination method

10 September 2018

E3 ubiquitin ligase that recognizes sugar chains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WTX6&geneProductId=UniProtKB:Q9WTX6

determination method

cell population proliferation

determination method

1 reference

14 February 2019

Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

protein monoubiquitination

determination method

1 reference

14 February 2019

Calmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

protein ubiquitination

determination method

3 references

apoptotic process

determination method

1 reference

14 February 2019

Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

ubiquitin-dependent protein catabolic process

determination method

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

E3 ubiquitin ligase that recognizes sugar chains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

proteasome-mediated ubiquitin-dependent protein catabolic process

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WTX6

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000031697

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000031697

ENSMUSP00000114959

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000114959

ENSMUSP00000121608

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000121608

ENSMUSP00000122702

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000122702

ENSMUSP00000144845

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000144845

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