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(Q21981719)
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English
Deoxyribonuclease II alpha
mammalian protein found in Mus musculus
Dnase2a
lysosomal DNase II
acid DNase
DNase II alpha
deoxyribonuclease-2-alpha
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P56542
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
P56542
part of
Deoxyribonuclease II
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P56542
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P56542
encoded by
Dnase2a
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P56542
molecular function
deoxyribonuclease II activity
determination method
IDA
IEA
3 references
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P56542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P56542&geneProductId=UniProtKB:P56542
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P56542&geneProductId=UniProtKB:P56542
determination method
IEA
retrieved
24 April 2018
stated in
Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P56542&geneProductId=UniProtKB:P56542
determination method
IDA
nuclease activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P56542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IEA
endonuclease activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P56542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IEA
hydrolase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P56542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IEA
endodeoxyribonuclease activity
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IEA
deoxyribonuclease II activity
determination method
IBA
IDA
IEA
4 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P56542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IEA
retrieved
14 February 2019
stated in
Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IBA
cell component
lysosome
determination method
TAS
IEA
2 references
retrieved
14 February 2019
stated in
Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
TAS
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P56542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IEA
biological process
multicellular organism development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P56542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IEA
erythrocyte differentiation
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IMP
DNA metabolic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IEA
DNA catabolic process
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IMP
DNA catabolic process, endonucleolytic
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
IFN regulatory factor (IRF) 3/7-dependent and -independent gene induction by mammalian DNA that escapes degradation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IMP
apoptotic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P56542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IEA
apoptotic DNA fragmentation
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IBA
regulation of immune response
determination method
IGI
1 reference
retrieved
14 February 2019
stated in
Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56542
determination method
IGI
Identifiers
RefSeq protein ID
NP_034192
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
13423
NP_001355224
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
13423
NP_001355225
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
13423
UniProt protein ID
P56542
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P56542
Ensembl protein ID
ENSMUSP00000138203
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000138203
ENSMUSP00000003910
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000003910
ENSMUSP00000105366
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000105366
ENSMUSP00000117198
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000117198
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