(Q21981779)

English

Endothelin 1

mammalian protein found in Mus musculus

endothelin-1
Edn1
PPET1
preproendothelin-1

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P22387

Endothelin-like toxin family

1 reference

based on heuristic

inferred from protein domain or family

Endothelin-like toxin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein binding

determination method

1 reference

8 April 2019

The first inner loop of endothelin receptor type B is necessary for specific coupling to Galpha 13

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

endothelin A receptor binding

determination method

extracellular space

determination method

3 references

biological process

skeletal system development

determination method

1 reference

8 April 2019

Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway

determination method

1 reference

8 April 2019

A novel vasoactive peptide endothelin stimulates mitogenesis through inositol lipid turnover in Swiss 3T3 fibroblasts

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

response to amino acid

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

vasoconstriction

determination method

body fluid secretion

determination method

1 reference

8 April 2019

Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

multicellular organism aging

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

cellular response to interferon-gamma

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

response to leptin

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

cellular response to hypoxia

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

response to muscle stretch

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

cellular response to calcium ion

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

cellular response to transforming growth factor beta stimulus

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

positive regulation of renal sodium excretion

determination method

1 reference

8 April 2019

Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

blood vessel morphogenesis

determination method

1 reference

8 April 2019

Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

response to nicotine

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

in utero embryonic development

determination method

1 reference

8 April 2019

Temporal requirement of signaling cascade involving endothelin-1/endothelin receptor type A in branchial arch development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

heart development

determination method

1 reference

8 April 2019

Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

cartilage development

determination method

1 reference

8 April 2019

Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

rhythmic excitation

determination method

1 reference

8 April 2019

Impaired ventilatory responses to hypoxia and hypercapnia in mutant mice deficient in endothelin-1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

protein kinase C-activating G protein-coupled receptor signaling pathway

determination method

1 reference

8 April 2019

A novel vasoactive peptide endothelin stimulates mitogenesis through inositol lipid turnover in Swiss 3T3 fibroblasts

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

cellular response to glucocorticoid stimulus

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

branching involved in blood vessel morphogenesis

determination method

1 reference

8 April 2019

Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

G protein-coupled receptor signaling pathway

determination method

3 references

8 April 2019

beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

response to ozone

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

respiratory gaseous exchange by respiratory system

determination method

1 reference

8 April 2019

Endothelin in the central control of cardiovascular and respiratory functions

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

response to lipopolysaccharide

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

response to prostaglandin F

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

regulation of vasoconstriction

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

cellular response to interleukin-1

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

response to salt

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

middle ear morphogenesis

determination method

1 reference

8 April 2019

Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

dorsal/ventral pattern formation

determination method

1 reference

8 April 2019

Endothelin-1 regulates the dorsoventral branchial arch patterning in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

phospholipase D-activating G protein-coupled receptor signaling pathway

determination method

1 reference

8 April 2019

Endothelin stimulates phospholipase D in striatal astrocytes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

regulation of pH

determination method

1 reference

8 April 2019

Endothelin-1/endothelin-B receptor-mediated increases in NHE3 activity in chronic metabolic acidosis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

maternal process involved in parturition

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

neural crest cell development

determination method

response to testosterone

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

cellular response to tumor necrosis factor

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

response to activity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

response to dexamethasone

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

cellular response to peptide hormone stimulus

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

cellular response to fatty acid

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

cellular response to mineralocorticoid stimulus

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

positive regulation of cell population proliferation

determination method

3 references

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

8 April 2019

A novel vasoactive peptide endothelin stimulates mitogenesis through inositol lipid turnover in Swiss 3T3 fibroblasts

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

response to transforming growth factor beta

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

regulation of signaling receptor activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

determination method

regulation of glucose transmembrane transport

determination method

1 reference

8 April 2019

beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

regulation of blood pressure

determination method

5 references

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

8 April 2019

Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

8 April 2019

Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

8 April 2019

Endothelin in the central control of cardiovascular and respiratory functions

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22387

determination method

negative regulation of gene expression

determination method

1 reference

5 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22387&geneProductId=UniProtKB:P22387

determination method

positive regulation of NIK/NF-kappaB signaling

determination method

1 reference

5 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22387&geneProductId=UniProtKB:P22387

determination method

positive regulation of vascular associated smooth muscle cell proliferation

determination method

1 reference

5 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22387&geneProductId=UniProtKB:P22387

determination method

positive regulation of smooth muscle contraction

determination method

Endothelin-like toxin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P22387

Endothelin-like toxin, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P22387

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000021796

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000021796

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21981779&oldid=2023212595"