(Q21981918)

English

Fatty acid synthase

mammalian protein found in Mus musculus

Fasn
fatty acid synthase
type I Fatty Acid Synthase

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

NAD(P)-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

ACP-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

GroES-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Alpha/Beta hydrolase fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

S-adenosyl-L-methionine-dependent methyltransferase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Acyl transferase/acyl hydrolase/lysophospholipase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Malonyl-CoA ACP transacylase, ACP-binding

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Acyl transferase domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Phosphopantetheine binding ACP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Polyketide synthase, enoylreductase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Polyketide synthase, ketoreductase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Polyketide synthase, dehydratase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

thioesterase, subgroup

1 reference

based on heuristic

inferred from protein domain or family

Alcohol dehydrogenase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Beta-ketoacyl synthase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ketoacyl-synthetase, C-terminal extension, protein family

1 reference

based on heuristic

inferred from protein domain or family

Polyketide synthase, phosphopantetheine-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Methyltransferase type 12, protein family

1 reference

based on heuristic

inferred from protein domain or family

Beta-ketoacyl synthase, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Polyketide synthase, beta-ketoacyl synthase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

acyltransferases

1 reference

based on heuristic

inferred from protein domain or family

Beta-ketoacyl synthase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

transferase activity

determination method

2 references

enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity

determination method

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19096&geneProductId=UniProtKB:P19096

determination method

3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

[acyl-carrier-protein] S-acetyltransferase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

hydrolase activity, acting on ester bonds

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

[acyl-carrier-protein] S-malonyltransferase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

myristoyl-[acyl-carrier-protein] hydrolase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

catalytic activity

determination method

2 references

enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity

determination method

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19096&geneProductId=UniProtKB:P19096

determination method

3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

oleoyl-[acyl-carrier-protein] hydrolase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

oxidoreductase activity

determination method

2 references

3-oxoacyl-[acyl-carrier-protein] synthase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

acyl-[acyl-carrier-protein] hydrolase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

hydrolase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

palmitoyl-[acyl-carrier-protein] hydrolase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

identical protein binding

determination method

1 reference

31 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19096&geneProductId=UniProtKB:P19096

determination method

protein homodimerization activity

determination method

1 reference

31 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19096&geneProductId=UniProtKB:P19096

determination method

determination method

1 reference

31 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19096&geneProductId=UniProtKB:P19096

determination method

phosphopantetheine binding

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

fatty acid synthase activity

determination method

4 references

31 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19096&geneProductId=UniProtKB:P19096

determination method

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19096&geneProductId=UniProtKB:P19096

determination method

31 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19096&geneProductId=UniProtKB:P19096

determination method

31 January 2018

Kr-pok increases FASN expression by modulating the DNA binding of SREBP-1c and Sp1 at the proximal promoter

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19096&geneProductId=UniProtKB:P19096

determination method

fatty acid synthase activity

determination method

6 references

14 February 2019

Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

14 February 2019

Kr-pok increases FASN expression by modulating the DNA binding of SREBP-1c and Sp1 at the proximal promoter

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

S-acetyltransferase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

S-malonyltransferase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

Golgi apparatus

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

plasma membrane

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

glycogen granule

determination method

1 reference

14 February 2019

Surfactant lipid synthesis and lamellar body formation in glycogen-laden type II cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

determination method

1 reference

31 January 2018

A mitochondrial protein compendium elucidates complex I disease biology

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19096&geneProductId=UniProtKB:P19096

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

determination method

3 references

determination method

1 reference

14 February 2019

A mitochondrial protein compendium elucidates complex I disease biology

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

biological process

cellular response to interleukin-4

determination method

1 reference

14 February 2019

Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

lipid metabolism

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

fatty acid metabolic process

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

mammary gland development

determination method

1 reference

14 February 2019

Fatty acid synthase is required for mammary gland development and milk production during lactation

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

acetyl-CoA metabolic process

determination method

1 reference

31 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19096&geneProductId=UniProtKB:P19096

determination method

fatty acid biosynthetic process

determination method

3 references

31 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19096&geneProductId=UniProtKB:P19096

determination method

31 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19096&geneProductId=UniProtKB:P19096

determination method

31 January 2018

Kr-pok increases FASN expression by modulating the DNA binding of SREBP-1c and Sp1 at the proximal promoter

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19096&geneProductId=UniProtKB:P19096

determination method

fatty acid biosynthetic process

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

14 February 2019

Kr-pok increases FASN expression by modulating the DNA binding of SREBP-1c and Sp1 at the proximal promoter

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

ether lipid biosynthetic process

determination method

1 reference

14 February 2019

Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

tissue development

determination method

1 reference

14 February 2019

Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

neutrophil differentiation

determination method

1 reference

14 February 2019

Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

monocyte differentiation

determination method

1 reference

14 February 2019

Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

macromolecule metabolic process

determination method

1 reference

14 February 2019

Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

cell development

determination method

1 reference

14 February 2019

Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

establishment of endothelial intestinal barrier

determination method

1 reference

14 February 2019

Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19096

determination method

Beta-ketoacyl synthase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Polyketide synthase, enoylreductase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Polyketide synthase, ketoreductase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Beta-ketoacyl synthase, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Polyketide synthase, dehydratase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Polyketide synthase, phosphopantetheine-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Polyketide synthase, beta-ketoacyl synthase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Acyl transferase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

thioesterase domain (polyketide / fatty acid synthase)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Phosphopantetheine binding ACP domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Beta-ketoacyl synthase, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Methyltransferase type 12

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Phosphopantetheine attachment site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Alcohol dehydrogenase, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Ketoacyl-synthetase, C-terminal extension

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19096

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000052872

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000052872

ENSMUSP00000145585

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000145585

ENSMUSP00000146068

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000146068

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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