(Q21982871)

glucocorticoid receptor

1 reference

Zinc finger, NHR/GATA-type

1 reference

Nuclear hormone receptor, ligand-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, nuclear hormone receptor-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

protein dimerization activity

1 reference

8 April 2019

Glucocorticoids, TGF-beta, and embryonic mouse salivary gland morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

DNA-binding transcription factor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

glucocorticoid receptor activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

Dyrk1A potentiates steroid hormone-induced transcription via the chromatin remodeling factor Arip4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

Abnormal gene expression and regulation in the liver of jvs mice with systemic carnitine deficiency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

Elevated expression of Bcl-2 and Bcl-x by intestinal intraepithelial lymphocytes: resistance to apoptosis by glucocorticoids and irradiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

nuclear receptor activity

4 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06537&geneProductId=UniProtKB:P06537

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06537&geneProductId=UniProtKB:P06537

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

steroid hormone receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 references

8 April 2019

Androgen receptor interactions with Oct-1 and Brn-1 are physically and functionally distinct

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

A novel protein, CHRONO, functions as a core component of the mammalian circadian clock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

Cryptochromes mediate rhythmic repression of the glucocorticoid receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

REV-ERBα influences the stability and nuclear localization of the glucocorticoid receptor.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

Hsp90 protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

double-stranded DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

transcription coactivator activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

transcription factor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

Hsp70 protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

receptor tyrosine kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

heat shock protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

protein homodimerization activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

sequence-specific DNA binding

protein-containing complex binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

protein heterodimerization activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

REV-ERBα influences the stability and nuclear localization of the glucocorticoid receptor.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

1 reference

8 April 2019

Elevated expression of Bcl-2 and Bcl-x by intestinal intraepithelial lymphocytes: resistance to apoptosis by glucocorticoids and irradiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

intracellular anatomical structure

1 reference

31 October 2017

Elevated expression of Bcl-2 and Bcl-x by intestinal intraepithelial lymphocytes: resistance to apoptosis by glucocorticoids and irradiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06537&geneProductId=UniProtKB:P06537

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

Abnormal gene expression and regulation in the liver of jvs mice with systemic carnitine deficiency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

Large-scale identification of mammalian proteins localized to nuclear sub-compartments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

microtubule organizing center

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

protein-containing complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

glutamatergic synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

postsynaptic density, intracellular component

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

cellular response to steroid hormone stimulus

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

regulation of gluconeogenesis

1 reference

8 April 2019

Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

regulation of transcription, DNA-templated

glucocorticoid mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

regulation of glucocorticoid biosynthetic process

1 reference

8 April 2019

Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

glucocorticoid metabolic process

1 reference

8 April 2019

The glucocorticoid receptor is essential for maintaining basal and dexamethasone-induced repression of the murine corticosteroid-binding globulin gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

adrenal gland development

1 reference

8 April 2019

Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

mammary gland duct morphogenesis

1 reference

8 April 2019

The mineralocorticoid receptor may compensate for the loss of the glucocorticoid receptor at specific stages of mammary gland development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

positive regulation of neuron apoptotic process

1 reference

8 April 2019

Subtle shifts in the ratio between pro- and antiapoptotic molecules after activation of corticosteroid receptors decide neuronal fate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

1 reference

8 April 2019

Luman/CREB3 recruitment factor regulates glucocorticoid receptor activity and is essential for prolactin-mediated maternal instinct

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

negative regulation of glucocorticoid mediated signaling pathway

IGI

1 reference

31 October 2017

Discovery of glucocorticoid receptor-beta in mice with a role in metabolism

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06537&geneProductId=UniProtKB:P06537

glucocorticoid receptor signaling pathway

5 references

8 April 2019

Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

Paracrine glucocorticoid activity produced by mouse thymic epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

Dyrk1A potentiates steroid hormone-induced transcription via the chromatin remodeling factor Arip4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

8 April 2019

microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

steroid hormone mediated signaling pathway

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06537&geneProductId=UniProtKB:P06537

transcription by RNA polymerase II

1 reference

31 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06537&geneProductId=UniProtKB:P06537

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

transcription, DNA-templated

3 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06537&geneProductId=UniProtKB:P06537

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06537&geneProductId=UniProtKB:P06537

31 October 2017

Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06537&geneProductId=UniProtKB:P06537

cellular response to dexamethasone stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

cellular response to transforming growth factor beta stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

cellular response to glucocorticoid stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

chromatin organization

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

regulation of glucose metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

positive regulation of glutamate secretion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

negative regulation of synaptic plasticity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

negative regulation of apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

negative regulation of vascular permeability

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

response to arsenic-containing substance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

positive regulation of dendritic spine development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

positive regulation of cell growth involved in cardiac muscle cell development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

positive regulation of pri-miRNA transcription by RNA polymerase II

1 reference

14 January 2019

microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06537&geneProductId=UniProtKB:P06537

positive regulation of glucocorticoid receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06537

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2869

Nuclear hormone receptor, ligand-binding domain

English

retrieved

17 August 2016

has part(s)

1 reference

nuclear hormone receptor-type zinc finger

1 reference

Identifiers

1 reference

21 May 2022

1 reference

21 May 2022

1 reference

21 May 2022

1 reference

21 May 2022

1 reference

21 May 2022

1 reference

21 May 2022

1 reference

21 May 2022

1 reference

21 May 2022

1 reference

21 May 2022

1 reference

21 May 2022

1 reference

21 May 2022

1 reference

21 May 2022

1 reference

21 May 2022

1 reference

21 May 2022

1 reference

21 May 2022

1 reference

21 May 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016