(Q21982984)

Dbl homology (DH) domain superfamily

1 reference

Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II

1 reference

VPS9 domain superfamily

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

VPS9 domain, protein family

1 reference

inferred from protein domain or family

Dbl homology (DH) domain, protein family

1 reference

inferred from protein domain or family

Regulator of chromosome condensation, RCC1, protein family

1 reference

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

protein homodimerization activity

ISS

GTPase activator activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

guanyl-nucleotide exchange factor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

protein serine/threonine kinase activator activity

IPI

1 reference

14 February 2019

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

identical protein binding

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

cell component

vesicle

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

14 February 2019

Alsin is partially associated with centrosome in human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

postsynaptic density

1 reference

14 February 2019

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

ruffle

1 reference

14 February 2019

Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

dendritic spine

1 reference

14 February 2019

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

dendrite

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

lamellipodium

1 reference

14 February 2019

Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

protein-containing complex

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

14 February 2019

Alsin is partially associated with centrosome in human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

growth cone

1 reference

14 February 2019

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

neuron projection morphogenesis

ISS

synaptic transmission, glutamatergic

1 reference

14 February 2019

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

locomotory behavior

vesicle organization

1 reference

14 February 2019

Alsin is partially associated with centrosome in human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

regulation of GTPase activity

1 reference

14 February 2019

Alsin is partially associated with centrosome in human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

in utero embryonic development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

behavioral fear response

1 reference

14 February 2019

Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

response to oxidative stress

1 reference

14 February 2019

Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

endosomal transport

positive regulation of GTPase activity

2 references

1 reference

14 February 2019

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

neuromuscular junction development

1 reference

14 February 2019

Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

lysosomal transport

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

regulation of Rho protein signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

1 reference

14 February 2019

protein homooligomerization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0

positive regulation of protein kinase activity

ISS

positive regulation of protein serine/threonine kinase activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q920R0