(Q21983233)

http://www.ebi.ac.uk/interpro/protein/Q9QZ59

DM DNA-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QZ59

DM DNA-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

protein homodimerization activity

1 reference

24 April 2018

Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QZ59&geneProductId=UniProtKB:Q9QZ59

RNA polymerase II transcription regulatory region sequence-specific DNA binding

IDA

1 reference

14 February 2019

Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

protein heterodimerization activity

IDA

1 reference

24 April 2018

Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QZ59&geneProductId=UniProtKB:Q9QZ59

1 reference

14 February 2019

Interaction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ line

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

DNA-binding transcription activator activity, RNA polymerase II-specific

IDA

1 reference

14 February 2019

Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

cis-regulatory region sequence-specific DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

DNA-binding transcription factor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

1 reference

14 February 2019

DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

6 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QZ59&geneProductId=UniProtKB:Q9QZ59

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QZ59&geneProductId=UniProtKB:Q9QZ59

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QZ59&geneProductId=UniProtKB:Q9QZ59

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QZ59&geneProductId=UniProtKB:Q9QZ59

24 April 2018

Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QZ59&geneProductId=UniProtKB:Q9QZ59

24 April 2018

DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QZ59&geneProductId=UniProtKB:Q9QZ59

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

negative regulation of meiotic nuclear division

IBA

biological process

1 reference

24 April 2018

The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QZ59&geneProductId=UniProtKB:Q9QZ59

regulation of nodal signaling pathway

1 reference

14 February 2019

Interaction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ line

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells

male sex differentiation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

developmental process involved in reproduction

1 reference

14 February 2019

Cell type-autonomous and non-autonomous requirements for Dmrt1 in postnatal testis differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

male germ cell proliferation

IGI

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

positive regulation of male gonad development

1 reference

14 February 2019

DMRT1 prevents female reprogramming in the postnatal mammalian testis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QZ59&geneProductId=UniProtKB:Q9QZ59

1 reference

24 April 2018

DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QZ59&geneProductId=UniProtKB:Q9QZ59

DMRT1 prevents female reprogramming in the postnatal mammalian testis

Sertoli cell development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

negative regulation of transcription by RNA polymerase II

3 references

14 February 2019

Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

1 reference

14 February 2019

Cell type-autonomous and non-autonomous requirements for Dmrt1 in postnatal testis differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells

male sex determination

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

positive regulation of mitotic nuclear division

1 reference

14 February 2019

The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

1 reference

14 February 2019

Cell type-autonomous and non-autonomous requirements for Dmrt1 in postnatal testis differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

positive regulation of meiosis I

1 reference

24 April 2018

DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QZ59&geneProductId=UniProtKB:Q9QZ59

Cell type-autonomous and non-autonomous requirements for Dmrt1 in postnatal testis differentiation

male gonad development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

positive regulation of transcription by RNA polymerase II

3 references

14 February 2019

Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

1 reference

14 February 2019

Cell type-autonomous and non-autonomous requirements for Dmrt1 in postnatal testis differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

transcription by RNA polymerase II

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QZ59&geneProductId=UniProtKB:Q9QZ59

male germ cell proliferation

3 references

14 February 2019

The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QZ59

negative regulation of meiotic nuclear division

IBA

DM DNA-binding domain

1 reference

stated in

InterPro Release 71.0