(Q21983365)

http://www.ebi.ac.uk/interpro/protein/P43406

integrin alpha chain

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P43406

Integrin alpha, N-terminal

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P43406

Integrin alpha beta-propellor, protein family

1 reference

Integrin alpha-2, protein family

1 reference

FG-GAP repeat, protein family

1 reference

Integrin alpha chain, C-terminal cytoplasmic region, conserved site, protein family

1 reference

insulin-like growth factor I binding

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

protein heterodimerization activity

1 reference

9 May 2019

Alpha (v) integrins license regulatory T cells to apoptotic cells and self-associated antigens

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

transforming growth factor beta binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

A novel protein kinase C alpha-dependent signal to ERK1/2 activated by alphaVbeta3 integrin in osteoclasts and in Chinese hamster ovary (CHO) cells

ISS

protein kinase C binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

integral component of membrane

C-X3-C chemokine binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

Morphofunctional studies of the glomerular wall in mice lacking entactin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

integrin alphav-beta3 complex

3 references

9 May 2019

Cloning and characterisation of ITGAV, the genomic sequence for human cell adhesion protein (vitronectin) receptor alpha subunit, CD51

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

integrin alphav-beta6 complex

1 reference

24 April 2018

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43406&geneProductId=UniProtKB:P43406

integrin alphav-beta5 complex

integrin alphav-beta8 complex

integrin alphav-beta6 complex

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

positive regulation of cell adhesion

biological process

negative regulation of lipoprotein metabolic process

detection of molecule of bacterial origin

1 reference

9 May 2019

Subversion of monocyte functions by coxiella burnetii: impairment of the cross-talk between alphavbeta3 integrin and CR3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

positive regulation of osteoblast proliferation

1 reference

9 May 2019

CYR61 regulates BMP-2-dependent osteoblast differentiation through the {alpha}v{beta}3 integrin/integrin-linked kinase/ERK pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

release of sequestered calcium ion into cytosol

1 reference

9 May 2019

A novel protein kinase C alpha-dependent signal to ERK1/2 activated by alphaVbeta3 integrin in osteoclasts and in Chinese hamster ovary (CHO) cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

trophoblast giant cell differentiation

1 reference

9 May 2019

Csf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

positive regulation of cell migration

1 reference

9 May 2019

CYR61 regulates BMP-2-dependent osteoblast differentiation through the {alpha}v{beta}3 integrin/integrin-linked kinase/ERK pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

A novel protein kinase C alpha-dependent signal to ERK1/2 activated by alphaVbeta3 integrin in osteoclasts and in Chinese hamster ovary (CHO) cells

IMP

ERK1 and ERK2 cascade

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

Collagen IV contributes to nitric oxide-induced angiogenesis of lung endothelial cells

response to nitric oxide

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

negative regulation of entry of bacterium into host cell

1 reference

9 May 2019

Expression pattern of alphavbeta3 and alphavbeta5 integrin mRNA in mouse fetal gonads

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

multicellular organism development

NAS

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

Alphavbeta3-integrin antagonists inhibit thrombin-induced proliferation and focal adhesion formation in smooth muscle cells

focal adhesion assembly

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alphav integrins

blood vessel development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

positive regulation of cell population proliferation

IMP

extrinsic apoptotic signaling pathway in absence of ligand

1 reference

9 May 2019

Unoccupied alpha(v)beta3 integrin regulates osteoclast apoptosis by transmitting a positive death signal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

1 reference

9 May 2019

Role of sperm alphavbeta3 integrin in mouse fertilization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

negative regulation of lipid storage

NAS

negative regulation of lipid transport

regulation of phagocytosis

4 references

9 May 2019

Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

3 references

9 May 2019

Cloning and characterisation of ITGAV, the genomic sequence for human cell adhesion protein (vitronectin) receptor alpha subunit, CD51

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin

inflammatory response

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

regulation of bone resorption

1 reference

9 May 2019

A novel protein kinase C alpha-dependent signal to ERK1/2 activated by alphaVbeta3 integrin in osteoclasts and in Chinese hamster ovary (CHO) cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

negative regulation of macrophage derived foam cell differentiation

1 reference

9 May 2019

Acute cellular rejection following human heart transplantation is associated with increased expression of vitronectin receptor (integrin alphavbeta3)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

endothelial cell migration

1 reference

9 May 2019

Acute cellular rejection following human heart transplantation is associated with increased expression of vitronectin receptor (integrin alphavbeta3)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

cell adhesion mediated by integrin

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

apoptotic cell clearance

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

Epithelial cells as phagocytes: apoptotic epithelial cells are engulfed by mammary alveolar epithelial cells and repress inflammatory mediator release

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

9 May 2019

HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406

integrin-mediated signaling pathway

integrin-mediated signaling pathway

ISO

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43406