(Q28910190)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation (English)

2 references

7 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

Wingless-type MMTV integration site family, member 4

12 March 2020

main subject

1 reference

Wingless-type MMTV integration site family, member 5A

1 reference

Integrin alpha V

1 reference

Integrin beta 6

1 reference

Catenin (cadherin associated protein), beta 1

1 reference

Lymphoid enhancer binding factor 1

1 reference

Fermitin family member 1

1 reference

Integrin beta 1 (fibronectin receptor beta)

1 reference

author

Emanuel Rognoni

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Siegfried Ussar

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

John Mcgrath

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

author name string

Moritz Widmaier

2

2 references

7 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Madis Jakobson

3

2 references

7 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Raphael Ruppert

4

2 references

7 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Despoina Katsougkri

6

2 references

7 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Ralph T Böttcher

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Joey E Lai-Cheong

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Daniel B Rifkin

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Reinhard Fässler

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

language of work or name

English

0 references

publication date

30 March 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

2 references

7 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

volume

20

2 references

7 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

page(s)

350-359

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

issue

4

2 references

7 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

12 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3982140/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Kindlin 2 forms a transcriptional complex with β-catenin and TCF4 to enhance Wnt signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

The basement membrane of hair follicle stem cells is a muscle cell niche

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Kindlin-2 is required for myocyte elongation and is essential for myogenesis

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Kindlin-2 controls bidirectional signaling of integrins

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Kindlin-3 is essential for integrin activation and platelet aggregation

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

The Kindlins: subcellular localization and expression during murine development

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Making sense of latent TGFbeta activation

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Consequences of lack of beta 1 integrin gene expression in mice

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Defining the epithelial stem cell niche in skin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

RNAi screens in mice identify physiological regulators of oncogenic growth

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Epithelial stem cells, wound healing and cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Functional differences between kindlin-1 and kindlin-2 in keratinocytes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Paracrine TGF-β signaling counterbalances BMP-mediated repression in hair follicle stem cell activation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

SnapShot: hair follicle stem cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Multimeric system of 99mTc-labeled gold nanoparticles conjugated to c[RGDfK(C)] for molecular imaging of tumor α(v)β(3) expression.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Cell-extracellular matrix interactions in normal and diseased skin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Kindlin-1 and -2 have overlapping functions in epithelial cells implications for phenotype modification.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Wounding enhances epidermal tumorigenesis by recruiting hair follicle keratinocytes.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Epidermal stem cell diversity and quiescence

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Mast cell-derived particles deliver peripheral signals to remote lymph nodes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

The tale of transforming growth factor-beta (TGFbeta) signaling: a soigné enigma.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

The Kindlin protein family: new members to the club of focal adhesion proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Kindlin-1 Is required for RhoGTPase-mediated lamellipodia formation in keratinocytes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Loss-of-function FERMT1 mutations in kindler syndrome implicate a role for fermitin family homolog-1 in integrin activation.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Multi-stage chemical carcinogenesis in mouse skin: fundamentals and applications

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

An activating beta1 integrin mutation increases the conversion of benign to malignant skin tumors.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Kindler syndrome: a focal adhesion genodermatosis.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Colocalization of kindlin-1, kindlin-2, and migfilin at keratinocyte focal adhesion and relevance to the pathophysiology of Kindler syndrome.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Wnt4 inhibits beta-catenin/TCF signalling by redirecting beta-catenin to the cell membrane

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Unusual molecular findings in Kindler syndrome

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Analysis of integrin functions in peri-implantation embryos, hematopoietic system, and skin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Integrin-linked kinase is required for epidermal and hair follicle morphogenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Aggressive squamous cell carcinoma in Kindler syndrome

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

New roles for integrins in squamous-cell carcinoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

A novel mode for integrin-mediated signaling: tethering is required for phosphorylation of FAK Y397

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Stem cells of the skin epithelium

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Stem cells in the skin: waste not, Wnt not.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

A tumor-associated beta 1 integrin mutation that abrogates epithelial differentiation control

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Role of integrins in regulating epidermal adhesion, growth and differentiation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3982140

Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction.

3 June 2018

1 reference

Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis

21 January 2018

1 reference

Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours.

21 January 2018

1 reference

Role of the focal adhesion protein kindlin-1 in breast cancer growth and lung metastasis.

21 January 2018

1 reference

A keratin K5Cre transgenic line appropriate for tissue-specific or generalized Cre-mediated recombination.

21 January 2018

1 reference

Comparison of chemical carcinogen skin tumor induction efficacy in inbred, mutant, and hybrid strains of mice: morphologic variations of induced tumors and absence of a papillomavirus cocarcinogen.

21 January 2018

1 reference

Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis

21 January 2018

1 reference

Integrin-alphavbeta6, a putative receptor for foot-and-mouth disease virus, is constitutively expressed in ruminant airways

21 January 2018

1 reference

A comprehensive guide for the recognition and classification of distinct stages of hair follicle morphogenesis

21 January 2018

1 reference

12 December 2020

Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion

1 reference

12 December 2020

Protein repellent properties of covalently attached PEG coatings on nanostructured SiO(2)-based interfaces

1 reference

12 December 2020

Integrin β6-deficient mice show enhanced keratinocyte proliferation and retarded hair follicle regression after depilation

1 reference

12 December 2020

Sorting nexin 17 prevents lysosomal degradation of β1 integrins by binding to the β1-integrin tail

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.3490

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681597%20AND%20SRC:MED&resulttype=core&format=json