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Wnt4 inhibits beta-catenin/TCF signalling by redirecting beta-catenin to the cell membrane
scientific article published on March 2008
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scholarly article
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stated in
Europe PubMed Central
PMCID
2670395
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17976036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
title
Wnt4 inhibits beta-catenin/TCF signalling by redirecting beta-catenin to the cell membrane
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2670395
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17976036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
author
Vincent R Harley
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
2670395
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17976036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
author name string
Pascal Bernard
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2670395
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17976036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
Alice Fleming
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2670395
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17976036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
Arnaud Lacombe
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
2670395
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17976036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
Eric Vilain
series ordinal
5
1 reference
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Europe PubMed Central
PMCID
2670395
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17976036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
language of work or name
English
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publication date
1 March 2008
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Europe PubMed Central
PMCID
2670395
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17976036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
number of pages
11
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published in
Biology of the Cell
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Europe PubMed Central
PMCID
2670395
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17976036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
volume
100
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Europe PubMed Central
PMCID
2670395
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17976036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
issue
3
1 reference
stated in
Europe PubMed Central
PMCID
2670395
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17976036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
page(s)
167-177
1 reference
stated in
Europe PubMed Central
PMCID
2670395
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17976036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
describes a project that uses
ImageJ
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Europe PubMed Central
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11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2670395/fullTextXML
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R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6
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PubMed Central
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Diversity of LEF/TCF action in development and disease
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R-spondin1 is essential in sex determination, skin differentiation and malignancy.
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Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors
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Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination
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Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context
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Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression
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Balancing cell adhesion and Wnt signaling, the key role of beta-catenin
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R-Spondin proteins: a novel link to beta-catenin activation
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Mitogenic influence of human R-spondin1 on the intestinal epithelium
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6 September 2017
Noncanonical Wnt-4 signaling and EAF2 are required for eye development in Xenopus laevis.
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R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis
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Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions
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6 September 2017
Wnt-4 activates the canonical beta-catenin-mediated Wnt pathway and binds Frizzled-6 CRD: functional implications of Wnt/beta-catenin activity in kidney epithelial cells
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PubMed Central
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6 September 2017
Interactions between Sox9 and beta-catenin control chondrocyte differentiation
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6 September 2017
Convergence of Wnt, beta-catenin, and cadherin pathways
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6 September 2017
Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling
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A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling
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6 September 2017
Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
Secreted antagonists of the Wnt signalling pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
The Wnt signaling pathway and its role in tumor development
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6 September 2017
Expression and Function of the Developmental Gene Wnt-4 during Experimental Acute Renal Failure in Rats
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PubMed Central
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6 September 2017
CNP gene expression is activated by Wnt signaling and correlates with Wnt4 expression during renal injury
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
Wnt-4 deficiency alters mouse adrenal cortex function, reducing aldosterone production
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
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PubMed Central
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6 September 2017
Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin
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PubMed Central
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6 September 2017
Phosphorylation of Pax2 by the c-Jun N-terminal kinase and enhanced Pax2-dependent transcription activation
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6 September 2017
Curbing the nuclear activities of beta-catenin. Control over Wnt target gene expression
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6 September 2017
The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape
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6 September 2017
Ca(2+)/calmodulin-dependent protein kinase II is stimulated by Wnt and Frizzled homologs and promotes ventral cell fates in Xenopus
1 reference
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PubMed Central
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6 September 2017
Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
Female development in mammals is regulated by Wnt-4 signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
Identification of c-MYC as a target of the APC pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
Multistep signaling requirements for pituitary organogenesis in vivo
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
Wnt signaling: a common theme in animal development
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
Modulation of embryonic intracellular Ca2+ signaling by Wnt-5A.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
Stabilization of beta-catenin by genetic defects in melanoma cell lines
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
A member of the Frizzled protein family mediating axis induction by Wnt-5A
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
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6 September 2017
Xwnt-5A: a maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
retrieved
6 September 2017
Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
retrieved
6 September 2017
Identification of distinct classes and functional domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
retrieved
6 September 2017
Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
retrieved
29 September 2017
Male-specific cell migration into the developing gonad.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
retrieved
27 June 2018
The partial female to male sex reversal in Wnt-4-deficient females involves induced expression of testosterone biosynthetic genes and testosterone production, and depends on androgen action.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
retrieved
3 September 2018
Endothelial and steroidogenic cell migration are regulated by WNT4 in the developing mammalian gonad
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
retrieved
3 September 2018
Divergent vascular mechanisms downstream of Sry establish the arterial system in the XY gonad
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
retrieved
3 September 2018
Wnt signaling controls the phosphorylation status of beta-catenin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
retrieved
3 September 2018
The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670395
retrieved
3 September 2018
Identifiers
DOI
10.1042/BC20070072
1 reference
stated in
Europe PubMed Central
PMCID
2670395
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17976036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
PMCID
2670395
1 reference
stated in
Europe PubMed Central
PMCID
2670395
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17976036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
PubMed ID
17976036
1 reference
stated in
Europe PubMed Central
PMCID
2670395
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17976036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
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