(Q24308067)

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Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression

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Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression (English)

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LDL receptor related protein 6

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GOA release 2020-03-11

canonical Wnt signaling pathway

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GOA release 2020-03-11

Wingless-type MMTV integration site family, member 1

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GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Frizzled class receptor 8

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GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Wingless-type MMTV integration site family, member 3A

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Ju-Suk Nam

1

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Taryn J Turcotte

2

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Peter F Smith

3

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Sangdun Choi

4

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Jeong Kyo Yoon

5

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language of work or name

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publication date

12 May 2006

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Journal of Biological Chemistry

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281

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19

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13247-57

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Mechanisms of Wnt signaling in development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Frizzleds: new members of the superfamily of G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

WNT-frizzled signaling via cyclic GMP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

The promise and perils of Wnt signaling through beta-catenin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

The WNT/calcium pathway: biochemical mediators, tools and future requirements

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

C. elegans LIN-18 is a Ryk ortholog and functions in parallel to LIN-17/Frizzled in Wnt signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Wnt-mediated axon guidance via the Drosophila Derailed receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Isolation of a candidate gene for Norrie disease by positional cloning

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Isolation and characterization of a candidate gene for Norrie disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Mitogenic influence of human R-spondin1 on the intestinal epithelium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Wnt proteins are lipid-modified and can act as stem cell growth factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

The bHLH regulator pMesogenin1 is required for maturation and segmentation of paraxial mesoderm

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

The bHLH class protein pMesogenin1 can specify paraxial mesoderm phenotypes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Fibroblast growth factors and their receptors: an information network controlling tissue growth, morphogenesis and repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Wnt-3a regulates somite and tailbud formation in the mouse embryo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

The CCN family: a new stimulus package

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Connective-tissue growth factor modulates WNT signalling and interacts with the WNT receptor complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Xenopus Cyr61 regulates gastrulation movements and modulates Wnt signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Expression pattern of the mouse T gene and its role in mesoderm formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

LDL-receptor-related proteins in Wnt signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Secreted antagonists of the Wnt signalling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

A new secreted protein that binds to Wnt proteins and inhibits their activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Role of heparan sulfate proteoglycans in cell-cell signaling in Drosophila

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Regulation of Wnt signaling and embryo patterning by an extracellular sulfatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

Functions of heparan sulfate proteoglycans in cell signaling during development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508324200

21 January 2018

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