Wikidata

(Q21981588)

English

Frizzled class receptor 8

mammalian protein found in Mus musculus

  • fz-8
  • frizzled-8
  • Fzd8
  • frizzled homolog 8
In more languages

Statements

molecular function
protein binding
determination method
IPI
11 references
retrieved
14 February 2019
stated in
Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth
GOA
curator
UniProt
UniProt protein ID
Q61091
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IPI
retrieved
14 February 2019
stated in
Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled
GOA
curator
UniProt
UniProt protein ID
Q61091
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IPI
retrieved
14 February 2019
stated in
Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IPI
retrieved
14 February 2019
stated in
Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IPI
retrieved
14 February 2019
stated in
ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IPI
retrieved
14 February 2019
stated in
LDL-receptor-related proteins in Wnt signal transduction
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IPI
retrieved
14 February 2019
stated in
Structural Studies of Wnts and Identification of an LRP6 Binding Site
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IPI
retrieved
14 February 2019
stated in
Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IPI
retrieved
14 February 2019
stated in
Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IPI
retrieved
14 February 2019
stated in
SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IPI
retrieved
14 February 2019
stated in
IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IPI
cell component
biological process
canonical Wnt signaling pathway
determination method
IDA
IGI
IEA
IMP
ISO
7 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091
determination method
ISO
retrieved
24 April 2018
stated in
Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091
determination method
IMP
retrieved
24 April 2018
stated in
Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091
determination method
IMP
retrieved
24 April 2018
stated in
Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091
determination method
IMP
retrieved
24 April 2018
stated in
Analysis of combinatorial effects of Wnts and Frizzleds on beta-catenin/armadillo stabilization and Dishevelled phosphorylation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091
determination method
IGI
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091
determination method
IEA
retrieved
24 April 2018
stated in
Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61091&geneProductId=UniProtKB:Q61091
determination method
IDA
canonical Wnt signaling pathway
determination method
IBA
IDA
IEA
IGI
IMP
ISO
8 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
ISO
retrieved
14 February 2019
stated in
Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IMP
retrieved
14 February 2019
stated in
Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IMP
retrieved
14 February 2019
stated in
Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IMP
retrieved
14 February 2019
stated in
Analysis of combinatorial effects of Wnts and Frizzleds on beta-catenin/armadillo stabilization and Dishevelled phosphorylation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IGI
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IEA
retrieved
14 February 2019
stated in
Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61091
determination method
IBA

Identifiers

 
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