(Q24303393)

sclerostin

1 reference

LDL receptor related protein 6

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negative regulation of canonical Wnt signaling pathway

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Frizzled class receptor 8

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Journal of Biological Chemistry

author name string

Mikhail Semënov

series ordinal

1

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Keiko Tamai

series ordinal

2

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Xi He

series ordinal

3

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language of work or name

English

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publication date

22 July 2005

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published in

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volume

280

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page(s)

26770-5

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issue

29

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cites work

The natural history of sclerosteosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

A 52-kb deletion in the SOST-MEOX1 intergenic region on 17q12-q21 is associated with van Buchem disease in the Dutch population

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Sclerostin is a novel secreted osteoclast-derived bone morphogenetic protein antagonist with unique ligand specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Patients with Van Buchem disease, an osteosclerotic genetic disease, have elevated bone formation markers, higher bone density, and greater derived polar moment of inertia than normal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Sclerostin promotes the apoptosis of human osteoblastic cells: a novel regulation of bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

LRP5 and Wnt signaling: a union made for bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

High bone density due to a mutation in LDL-receptor-related protein 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

arrow encodes an LDL-receptor-related protein essential for Wingless signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

An LDL-receptor-related protein mediates Wnt signalling in mice

21 January 2018

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21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Wise, a context-dependent activator and inhibitor of Wnt signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Functional and structural diversity of the human Dickkopf gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Cloning of a novel member of the low-density lipoprotein receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

A mechanism for Wnt coreceptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Formation and function of Spemann's organizer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Prediction, conservation analysis, and structural characterization of mammalian mucin-type O-glycosylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

The WNT signalling modulator, Wise, is expressed in an interaction-dependent manner during hair-follicle cycling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504308200

21 January 2018

Identifiers

DOI

10.1074/JBC.M504308200

1 reference

Consolidated OpenCitations Corpus – April 2017

3463800

3463800

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference