(Q36405065)

14 August 2017

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title

New roles for integrins in squamous-cell carcinoma (English)

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14 August 2017

2

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14 August 2017

Sam M Janes

1

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PubMed ID

16498442

14 August 2017

language of work or name

English

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publication date

1 March 2006

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14 August 2017

Nature Reviews Cancer

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14 August 2017

6

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14 August 2017

175-183

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14 August 2017

3

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https://scigraph.springernature.com/pub.10.1038/nrc1817

14 August 2017

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cites work

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beta1 integrins regulate keratinocyte adhesion and differentiation by distinct mechanisms

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Profiling early head and neck cancer

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Contribution of stem cells and differentiated cells to epidermal tumours

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Role of integrins in regulating epidermal adhesion, growth and differentiation

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Integrin signalling during tumour progression

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Loss of alpha 6 and beta 4 integrin subunits coincides with loss of basement membrane components in oral squamous cell carcinomas

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Expression of beta 1 integrin receptors in transformed mouse epidermal keratinocytes: upregulation of alpha 5 beta 1 in spindle carcinoma cells

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Changes in the expression of alpha v integrins in oral squamous cell carcinomas

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Switch from alphavbeta5 to alphavbeta6 integrin expression protects squamous cell carcinomas from anoikis

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A tumor-associated beta 1 integrin mutation that abrogates epithelial differentiation control

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Signaling via beta1 integrins and mitogen-activated protein kinase determines human epidermal stem cell fate in vitro

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A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis

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Changing Ligand Specificities of αvβ1 and αvβ3 Integrins by Swapping a Short Diverse Sequence of the β Subunit

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Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

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Stem cells, cancer, and cancer stem cells

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Sequence variation in the I-like domain of the beta1 integrin subunit in human oral squamous cell carcinomas

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The role of platelet collagen receptor (glycoprotein Ia/IIa; integrin alpha2 beta1) polymorphisms in thrombotic disease

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Different consequences of beta1 integrin deletion in neonatal and adult mouse epidermis reveal a context-dependent role of integrins in regulating proliferation, differentiation, and intercellular communication.

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Conditional ablation of beta1 integrin in skin. Severe defects in epidermal proliferation, basement membrane formation, and hair follicle invagination

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Stem cell depletion through epidermal deletion of Rac1.

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Molecular mechanisms of "detachment-induced apoptosis--Anoikis".

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Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis

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Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins

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The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis

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Regulation of cell death protease caspase-9 by phosphorylation

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The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells

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Role of integrins in cell invasion and migration

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Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression.

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Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis

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31 March 2020

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Expression of activated MEK1 in differentiating epidermal cells is sufficient to generate hyperproliferative and inflammatory skin lesions

31 March 2020

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Mek1 alters epidermal growth and differentiation

31 March 2020

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Regulation of interleukin-1alpha expression by integrins and epidermal growth factor receptor in keratinocytes from a mouse model of inflammatory skin disease

31 March 2020

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31 March 2020

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The α2 and α5 integrin genes: identification of transcription factors that regulate promoter activity in epidermal keratinocytes

31 March 2020

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Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1

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Type VII collagen is required for Ras-driven human epidermal tumorigenesis.

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRC1817

1 reference

PubMed ID

16498442

Dimensions Publication ID

14 August 2017

0 references

1 reference

PubMed ID

16498442