(Q21498209)

High mobility group box domain superfamily

1 reference

Lymphoid enhancer-binding factor 1

1 reference

High mobility group box domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CTNNB1 binding, N-teminal, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

DNA-binding transcription factor activity

5 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

16 July 2018

LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

16 July 2018

Alx4 binding to LEF-1 regulates N-CAM promoter activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

16 July 2018

The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

11 October 2018

Lymphoid enhancer-binding factor-1 binds and activates the recombination-activating gene-2 promoter together with c-Myb and Pax-5 in immature B cells

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

armadillo repeat domain binding

3 references

estrogen receptor binding

3 references

transcription factor binding

1 reference

14 February 2019

Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

RNA polymerase II cis-regulatory region sequence-specific DNA binding

IPI

2 references

10 September 2018

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

Lymphoid enhancer-binding factor-1 binds and activates the recombination-activating gene-2 promoter together with c-Myb and Pax-5 in immature B cells

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

gamma-catenin binding

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

4 references

16 July 2018

Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

16 July 2018

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

16 July 2018

Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

16 July 2018

Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

8 references

14 February 2019

Sox17 modulates Wnt3A/beta-catenin-mediated transcriptional activation of the Lef-1 promoter.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Alx4 binding to LEF-1 regulates N-CAM promoter activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Pax3 functions at a nodal point in melanocyte stem cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Thermodynamics of beta-catenin-ligand interactions: the roles of the N- and C-terminal tails in modulating binding affinity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Jerky/Earthbound facilitates cell-specific Wnt/Wingless signalling by modulating β-catenin-TCF activity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Chromatin protein HMGB2 regulates articular cartilage surface maintenance via beta-catenin pathway

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

1 reference

14 February 2019

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

sequence-specific DNA binding

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

16 July 2018

The Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

16 July 2018

Transcriptional analysis of Gli3 mutants identifies Wnt target genes in the developing hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

1 reference

16 July 2018

Pax3 functions at a nodal point in melanocyte stem cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

5 references

14 February 2019

Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

DNA-binding transcription factor activity

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Alx4 binding to LEF-1 regulates N-CAM promoter activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

sequence-specific DNA binding

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

The Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Transcriptional analysis of Gli3 mutants identifies Wnt target genes in the developing hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

RNA polymerase II cis-regulatory region sequence-specific DNA binding

3 references

14 February 2019

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Lymphoid enhancer-binding factor-1 binds and activates the recombination-activating gene-2 promoter together with c-Myb and Pax-5 in immature B cells

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

DNA-binding transcription activator activity, RNA polymerase II-specific

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Lymphoid enhancer-binding factor-1 binds and activates the recombination-activating gene-2 promoter together with c-Myb and Pax-5 in immature B cells

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

14 February 2019

Pax3 functions at a nodal point in melanocyte stem cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

16 July 2018

Shh expression is required for embryonic hair follicle but not mammary gland development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

16 July 2018

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

13 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

LEF-1 negatively controls interleukin-4 expression through a proximal promoter regulatory element

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

Shh expression is required for embryonic hair follicle but not mammary gland development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

transcription regulator complex

3 references

beta-catenin-TCF complex

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

transcription regulator complex

IC

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Alx4 binding to LEF-1 regulates N-CAM promoter activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Shh expression is required for embryonic hair follicle but not mammary gland development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

LEF-1 negatively controls interleukin-4 expression through a proximal promoter regulatory element

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Shh expression is required for embryonic hair follicle but not mammary gland development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

1 reference

14 February 2019

Wnt signaling interacts with Shh to regulate taste papilla development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

paraxial mesoderm formation

1 reference

16 July 2018

Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

T cell receptor V(D)J recombination

1 reference

14 February 2019

Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

mammary gland development

1 reference

16 July 2018

Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

negative regulation of interleukin-13 production

3 references

odontogenesis of dentin-containing tooth

3 references

14 February 2019

LEF1 is a critical epithelial survival factor during tooth morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

FGF4, a direct target of LEF1 and Wnt signaling, can rescue the arrest of tooth organogenesis in Lef1(-/-) mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Wnt signaling mediates regional specification in the vertebrate face

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

apoptotic process involved in blood vessel morphogenesis

1 reference

14 February 2019

WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

1 reference

16 July 2018

Wnt signaling mediates regional specification in the vertebrate face

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

neutrophil differentiation

3 references

negative regulation of interleukin-5 production

3 references

regulation of transcription, DNA-templated

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

dentate gyrus development

1 reference

16 July 2018

Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

apoptotic process involved in morphogenesis

1 reference

16 July 2018

LEF1 is a critical epithelial survival factor during tooth morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

transcription, DNA-templated

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

positive regulation of transcription, DNA-templated

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

regulation of Wnt signaling pathway

1 reference

14 February 2019

Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

embryonic limb morphogenesis

1 reference

16 July 2018

Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

hypothalamus development

1 reference

16 July 2018

branching involved in blood vessel morphogenesis

1 reference

16 July 2018

Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

trachea gland development

1 reference

16 July 2018

Submucosal gland development in the airway is controlled by lymphoid enhancer binding factor 1 (LEF1)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

forebrain neuroblast division

1 reference

16 July 2018

Wnt signaling mutants have decreased dentate granule cell production and radial glial scaffolding abnormalities

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis

sprouting angiogenesis

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth

BMP signaling pathway

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

regulation of cell-cell adhesion

1 reference

16 July 2018

Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

formation of radial glial scaffolds

1 reference

16 July 2018

Wnt signaling mutants have decreased dentate granule cell production and radial glial scaffolding abnormalities

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

epithelial to mesenchymal transition

1 reference

16 July 2018

TGFbeta3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

alpha-beta T cell differentiation

1 reference

16 July 2018

Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

canonical Wnt signaling pathway

negative regulation of transcription, DNA-templated

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

sensory perception of taste

1 reference

14 February 2019

Wnt signaling interacts with Shh to regulate taste papilla development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

3 references

1 reference

14 February 2019

Pax3 functions at a nodal point in melanocyte stem cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

negative regulation of interleukin-4 production

3 references

negative regulation of striated muscle tissue development

1 reference

14 February 2019

The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

Wnt signaling pathway

8 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

24 April 2018

Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

24 April 2018

Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

24 April 2018

Wnt signaling mediates regional specification in the vertebrate face

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

24 April 2018

Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

T-helper 1 cell differentiation

1 reference

14 February 2019

LEF-1 negatively controls interleukin-4 expression through a proximal promoter regulatory element

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

positive regulation of cell proliferation in bone marrow

3 references

anatomical structure regression

1 reference

14 February 2019

WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice

chorio-allantoic fusion

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

negative regulation of apoptotic process in bone marrow cell

3 references

1 reference

16 July 2018

Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature

vasculature development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

forebrain radial glial cell differentiation

1 reference

16 July 2018

Wnt signaling mutants have decreased dentate granule cell production and radial glial scaffolding abnormalities

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

neural crest cell migration

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

forebrain neuron differentiation

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1

hippocampus development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

positive regulation of transcription by RNA polymerase II

8 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

Wnt signaling interacts with Shh to regulate taste papilla development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

Activation of mouse RAG-2 promoter by Myc-associated zinc finger protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

Lymphoid enhancer-binding factor-1 binds and activates the recombination-activating gene-2 promoter together with c-Myb and Pax-5 in immature B cells

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

CNP gene expression is activated by Wnt signaling and correlates with Wnt4 expression during renal injury

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

10 September 2018

LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

steroid hormone mediated signaling pathway

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

negative regulation of cell-cell adhesion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

positive regulation of cell-cell adhesion

ISO

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

positive regulation of cell cycle process

ISO

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

secondary palate development

ISO

1 reference

14 February 2019

TGFbeta3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

Wnt signaling pathway

canonical Wnt signaling pathway

2 references

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Wnt signaling mediates regional specification in the vertebrate face

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

negative regulation of canonical Wnt signaling pathway

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27782&geneProductId=UniProtKB:P27782

3 references

14 February 2019

LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

epithelial to mesenchymal transition

regulation of transcription, DNA-templated

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

regulation of transcription by RNA polymerase II

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Alx4 binding to LEF-1 regulates N-CAM promoter activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

negative regulation of transcription, DNA-templated

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

positive regulation of transcription, DNA-templated

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

positive regulation of transcription by RNA polymerase II

9 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Wnt signaling interacts with Shh to regulate taste papilla development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Activation of mouse RAG-2 promoter by Myc-associated zinc finger protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Lymphoid enhancer-binding factor-1 binds and activates the recombination-activating gene-2 promoter together with c-Myb and Pax-5 in immature B cells

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

CNP gene expression is activated by Wnt signaling and correlates with Wnt4 expression during renal injury

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27782

CTNNB1 binding, N-teminal

has part(s)

1 reference

High mobility group box domain

1 reference