(Q28511944)

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

The Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program (English)

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

Catenin (cadherin associated protein), beta 1

1 reference

Lymphoid enhancer binding factor 1

1 reference

Hes family bHLH transcription factor 7

1 reference

Mesogenin 1

1 reference

author

Deborah L Chapman

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Michael Kyba

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

author name string

Rieko Ajima

4

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Michelina Iacovino

5

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Arica Beisaw

6

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Lionel Feigenbaum

7

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Jeong Kyo Yoon

9

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Ravindra B Chalamalasetty

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

William C Dunty

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Kristin K Biris

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Terry P Yamaguchi

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

language of work or name

English

0 references

publication date

12 July 2011

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

published in

Nature Communications

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

volume

2

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

page(s)

390

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

Notch is a critical component of the mouse somitogenesis oscillator and is essential for the formation of the somites

7 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

miR-155 inhibition sensitizes CD4+ Th cells for TREG mediated suppression

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Oscillatory lunatic fringe activity is crucial for segmentation of the anterior but not posterior skeleton

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Wnt3a links left-right determination with segmentation and anteroposterior axis elongation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clock

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Wnt3a plays a major role in the segmentation clock controlling somitogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Dynamic expression and essential functions of Hes7 in somite segmentation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Hes7: a bHLH-type repressor gene regulated by Notch and expressed in the presomitic mesoderm

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

The bHLH regulator pMesogenin1 is required for maturation and segmentation of paraxial mesoderm

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Wnt-3a regulates somite and tailbud formation in the mouse embryo

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Structure and function of helix-loop-helix proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

VISTA: computational tools for comparative genomics

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Cyclic Nrarp mRNA expression is regulated by the somitic oscillator but Nrarp protein levels do not oscillate.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

A conserved role for Hox paralog group 4 in regulation of hematopoietic progenitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Control of segment number in vertebrate embryos

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Segmental patterning of the vertebrate embryonic axis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Expression of Msgn1 in the presomitic mesoderm is controlled by synergism of WNT signalling and Tbx6.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Chromatin immunoprecipitation and microarray-based analysis of protein location

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Transcription under the control of nuclear Arm/beta-catenin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Clock regulatory elements control cyclic expression of Lunatic fringe during somitogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

The bHLH class protein pMesogenin1 can specify paraxial mesoderm phenotypes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Ascl1 and Neurog2 form novel complexes and regulate Delta-like3 (Dll3) expression in the neural tube

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Identification of oscillatory genes in somitogenesis from functional genomic analysis of a human mesenchymal stem cell model

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

The lunatic fringe gene is a target of the molecular clock linked to somite segmentation in avian embryos.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Waves of mouse Lunatic fringe expression, in four-hour cycles at two-hour intervals, precede somite boundary formation.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

lunatic fringe is an essential mediator of somite segmentation and patterning

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

Avian hairy gene expression identifies a molecular clock linked to vertebrate segmentation and somitogenesis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622708

A complex oscillating network of signaling genes underlies the mouse segmentation clock.

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1381

Dynamic expression of lunatic fringe suggests a link between notch signaling and an autonomous cellular oscillator driving somite segmentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1381

Wnt3a/beta-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1381

FGF signaling acts upstream of the NOTCH and WNT signaling pathways to control segmentation clock oscillations in mouse somitogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1381

FGF signaling controls somite boundary position and regulates segmentation clock control of spatiotemporal Hox gene activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1381

Mouse Ripply2 is downstream of Wnt3a and is dynamically expressed during somitogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1381

The negative regulation of Mesp2 by mouse Ripply2 is required to establish the rostro-caudal patterning within a somite.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1381

Periodic Lunatic fringe expression is controlled during segmentation by a cyclic transcriptional enhancer responsive to notch signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1381

Distinct regulatory elements direct delta1 expression in the nervous system and paraxial mesoderm of transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1381

Periodic notch inhibition by lunatic fringe underlies the chick segmentation clock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1381

Cdx4 is a direct target of the canonical Wnt pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1381

FusionDB: a database for in-depth analysis of prokaryotic gene fusion events

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1381

Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1381

A clock and wavefront model for control of the number of repeated structures during animal morphogenesis

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21750544

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance

1 reference

https://pubmed.ncbi.nlm.nih.gov/21750544

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A β-catenin gradient links the clock and wavefront systems in mouse embryo segmentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21750544

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS1381

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 February 2020

ADS bibcode

2011NatCo...2..390C

0 references

1024600547

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21750544%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

2 references