(Q21988621)

English

T-box 6

mammalian protein found in Mus musculus

Tbx6
T-box transcription factor TBX6
rib-vertebrae
T-box protein 6

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

p53-like transcription factor, DNA-binding

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P70327

Transcription factor, Brachyury

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P70327

T-box superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P70327

Transcription factor, T-box, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

DNA-binding transcription factor activity

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70327

determination method

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

1 reference

14 February 2019

Dll1 is a downstream target of Tbx6 in the paraxial mesoderm

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70327

determination method

determination method

biological process

cell fate specification

determination method

1 reference

14 February 2019

Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70327

determination method

multicellular organism development

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70327

determination method

somite rostral/caudal axis specification

determination method

1 reference

14 February 2019

Analysis of Ripply1/2-deficient mouse embryos reveals a mechanism underlying the rostro-caudal patterning within a somite

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70327

determination method

negative regulation of neuron maturation

determination method

1 reference

14 February 2019

Spatially coordinated kinase signaling regulates local axon degeneration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70327

determination method

signal transduction involved in regulation of gene expression

determination method

1 reference

14 February 2019

ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70327

determination method

negative regulation of neuron projection development

determination method

1 reference

14 February 2019

Spatially coordinated kinase signaling regulates local axon degeneration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70327

determination method

regulation of transcription, DNA-templated

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70327

determination method

negative regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70327

determination method

transcription, DNA-templated

determination method

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70327&geneProductId=UniProtKB:P70327

determination method

positive regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

The Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70327

determination method

negative regulation of DNA-binding transcription factor activity

determination method

1 reference

14 February 2019

Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70327

determination method

Transcription factor, T-box, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P70327

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000091579

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000091579

ENSMUSP00000126418

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000126418

Sitelinks

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Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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