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(Q21983860)
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Docking protein 2
mammalian protein found in Mus musculus
dok-R
FRIP
downstream of tyrosine kinase 2
docking protein 2
p56(dok-2)
Dok2
dok-related protein
IL-Four Receptor Interacting Protein
IL-four receptor-interacting protein
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O70469
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
O70469
part of
PH-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O70469
pleckstrin homology domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Dok1/2/3, PTB domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
IRS-type PTB domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O70469
encoded by
Dok2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O70469
molecular function
transmembrane receptor protein tyrosine kinase adaptor activity
determination method
IPI
1 reference
retrieved
14 February 2019
stated in
Independent SH2-binding sites mediate interaction of Dok-related protein with RasGTPase-activating protein and Nck
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70469
determination method
IPI
protein binding
determination method
IPI
1 reference
retrieved
14 February 2019
stated in
FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70469
determination method
IPI
cell component
intracellular anatomical structure
determination method
IEA
1 reference
retrieved
21 June 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O70469&geneProductId=UniProtKB:O70469
determination method
IEA
biological process
Ras protein signal transduction
determination method
IPI
1 reference
retrieved
14 February 2019
stated in
FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70469
determination method
IPI
MAPK cascade
determination method
TAS
1 reference
retrieved
5 June 2018
stated in
Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O70469&geneProductId=UniProtKB:O70469
determination method
TAS
transmembrane receptor protein tyrosine kinase signaling pathway
determination method
IPI
2 references
retrieved
14 February 2019
stated in
Independent SH2-binding sites mediate interaction of Dok-related protein with RasGTPase-activating protein and Nck
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70469
determination method
IPI
retrieved
14 February 2019
stated in
FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70469
determination method
IPI
negative regulation of MAPK cascade
determination method
TAS
1 reference
retrieved
14 February 2019
stated in
Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70469
determination method
TAS
has part(s)
pleckstrin homology domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O70469
IRS-type PTB domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O70469
Dok1/2/3, PTB domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O70469
Identifiers
RefSeq protein ID
NP_034201
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
13449
XP_011243245
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
13449
XP_017171323
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
13449
XP_036014327
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
13449
XP_036014328
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
13449
XP_036014329
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
13449
XP_036014330
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
13449
NP_001388209
1 reference
stated in
NCBI Gene
retrieved
20 February 2022
Entrez Gene ID
13449
NP_001388210
1 reference
stated in
NCBI Gene
retrieved
20 February 2022
Entrez Gene ID
13449
UniProt protein ID
O70469
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O70469
Ensembl protein ID
ENSMUSP00000022698
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000022698
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Multilingual sites
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