(Q21983878)

http://www.ebi.ac.uk/interpro/protein/Q8C147

Armadillo-type fold

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8C147

C2 domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8C147

membrane protein

1 reference

inferred from GOA cell component → membrane

Dedicator of cytokinesis C, C2 domain, protein family

1 reference

DHR-1 domain, protein family

1 reference

DHR-2 domain, protein family

1 reference

Dedicator of cytokinesis C/D, N-terminal domain, protein family

1 reference

LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

guanyl-nucleotide exchange factor activity

IPI

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

14 February 2019

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

1 reference

14 February 2019

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

lamellipodium membrane

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

negative regulation of T cell apoptotic process

biological process

1 reference

14 February 2019

DOCK8 is essential for T-cell survival and the maintenance of CD8+ T-cell memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

small GTPase mediated signal transduction

IMP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

immunological synapse formation

1 reference

14 February 2019

DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration

IMP

dendritic cell migration

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

14 February 2019

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

14 February 2019

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

positive regulation of establishment of T cell polarity

IGI

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

14 February 2019

LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

positive regulation of T cell migration

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

14 February 2019

LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C147