(Q21983880)

SH3-like domain superfamily

1 reference

Armadillo-type fold

1 reference

C2 domain superfamily

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Dedicator of cytokinesis, N-terminal domain, protein family

1 reference

DHR-1 domain, protein family

1 reference

DHR-2 domain, protein family

1 reference

SH3 domain, protein family

1 reference

GTPase activator activity

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

guanyl-nucleotide exchange factor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

2 references

T cell receptor binding

3 references

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

positive regulation of phagocytosis

biological process

1 reference

14 February 2019

The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

small GTPase mediated signal transduction

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

alpha-beta T cell activation

1 reference

14 February 2019

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

membrane raft polarization

1 reference

14 February 2019

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

negative thymic T cell selection

1 reference

14 February 2019

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

1 reference

14 February 2019

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

1 reference

14 February 2019

Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

alpha-beta T cell proliferation

1 reference

14 February 2019

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

1 reference

14 February 2019

The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

cytoskeleton organization

1 reference

14 February 2019

Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

myeloid dendritic cell activation involved in immune response

IDA

1 reference

14 February 2019

The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

positive thymic T cell selection

1 reference

14 February 2019

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

establishment of T cell polarity

1 reference

14 February 2019

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

immunological synapse formation

1 reference

14 February 2019

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

actin cytoskeleton organization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

1 reference

14 February 2019

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

positive regulation of Rac protein signal transduction

1 reference

14 February 2019

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

positive regulation of GTPase activity

IC

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5