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DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells
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scholarly article
1 reference
stated in
PubMed
PubMed ID
12871644
retrieved
31 January 2017
title
DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells
(English)
1 reference
stated in
PubMed
PubMed ID
12871644
retrieved
31 January 2017
main subject
Dedicator of cyto-kinesis 2
1 reference
stated in
GOA release 2020-03-11
membrane raft
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based on heuristic
inferred from title
author
Yoshinori Fukui
object named as
Yoshinori Fukui
series ordinal
7
0 references
author name string
Terukazu Sanui
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
12871644
retrieved
31 January 2017
Ayumi Inayoshi
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
12871644
retrieved
31 January 2017
Mayuko Noda
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
12871644
retrieved
31 January 2017
Eiko Iwata
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
12871644
retrieved
31 January 2017
Masahiro Oike
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
12871644
retrieved
31 January 2017
Takehiko Sasazuki
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
12871644
retrieved
31 January 2017
language of work or name
English
0 references
publication date
1 July 2003
1 reference
stated in
PubMed
PubMed ID
12871644
retrieved
31 January 2017
published in
Immunity
1 reference
stated in
PubMed
PubMed ID
12871644
retrieved
31 January 2017
volume
19
1 reference
stated in
PubMed
PubMed ID
12871644
retrieved
31 January 2017
issue
1
1 reference
stated in
PubMed
PubMed ID
12871644
retrieved
31 January 2017
page(s)
119–129
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stated in
PubMed
PubMed ID
12871644
retrieved
31 January 2017
cites work
Distinct patterns of membrane microdomain partitioning in Th1 and th2 cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effects of MHC gene dosage and allelic variation on T cell receptor selection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: quantitative imaging of raft accumulation in the immunological synapse
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The GTPase Rac-1 controls cell fate in the thymus by diverting thymocytes from positive to negative selection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The immunological synapse: a molecular machine controlling T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Positive Regulation of T Cell Activation and Integrin Adhesion by the Adapter Fyb/Slap
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac function and regulation during Drosophila development.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho GTPases and the actin cytoskeleton
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Rac1 by a Crk SH3-binding protein, DOCK180
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vav regulates peptide-specific apoptosis in thymocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human CD8+ T cells do not require the polarization of lipid rafts for activation and proliferation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential clustering of CD4 and CD3zeta during T cell recognition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell receptor signaling precedes immunological synapse formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrin-mediated long-term B cell retention in the splenic marginal zone.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective modulation of protein kinase C-theta during T-cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three-dimensional segregation of supramolecular activation clusters in T cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The common cytokine receptor gamma chain plays an essential role in regulating lymphoid homeostasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DOCK2 mediates T cell receptor-induced activation of Rac2 and IL-2 transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Actin Cytoskeleton and Lymphocyte Activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coupling of the TCR to integrin activation by Slap-130/Fyb.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T lymphocyte costimulation mediated by reorganization of membrane microdomains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulated nuclear import of Rel proteins in the Drosophila immune response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A receptor/cytoskeletal movement triggered by costimulation during T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Non-CD28 costimulatory molecules present in T cell rafts induce T cell costimulation by enhancing the association of TCR with rafts.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deficiency of small GTPase Rac2 affects T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900169-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1074-7613(03)00169-9
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4718098
OpenCitations bibliographic resource ID
4718098
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4718098
PubMed ID
12871644
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4718098
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