(Q52126964)

22 April 2018

title

The GTPase Rac-1 controls cell fate in the thymus by diverting thymocytes from positive to negative selection. (English)

1 reference

22 April 2018

0 references

Gomez M

1

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22 April 2018

Kioussis D

series ordinal

2

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22 April 2018

Cantrell DA

series ordinal

3

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22 April 2018

language of work or name

English

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publication date

1 November 2001

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22 April 2018

published in

Immunity

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22 April 2018

volume

15

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22 April 2018

page(s)

703-713

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22 April 2018

issue

5

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22 April 2018

T cell activation and the cytoskeleton

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Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

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Different functions of the GTPase Rho in prothymocytes and late pre-T cells

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Multiple p21ras effector pathways regulate nuclear factor of activated T cells.

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Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

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Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation.

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Opening a window on thymic positive selection: developmental changes in the influence of cosignaling by integrins and CD28 on selection events induced by TCR engagement

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Thymic depletion and peripheral activation of class I major histocompatibility complex-restricted T cells by soluble peptide in T-cell receptor transgenic mice

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7 January 2021

T cell deletion follows chronic antigen specific T cell activation in vivo

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7 January 2021

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

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7 January 2021

Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

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7 January 2021

Maturation versus death of developing double-positive thymocytes reflects competing effects on Bcl-2 expression and can be regulated by the intensity of CD28 costimulation

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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7 January 2021

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7 January 2021

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7 January 2021

Searching for a function for nuclear actin.

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7 January 2021

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7 January 2021

MAP-kinase signaling pathways in T cells

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7 January 2021

The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes

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7 January 2021

Constitutive activation of integrin alpha 4 beta 1 defines a unique stage of human thymocyte development

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7 January 2021

Selection of the T cell repertoire.

1 reference

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7 January 2021

Signal-regulated activation of serum response factor is mediated by changes in actin dynamics

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7 January 2021

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice

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https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900235-7

7 January 2021

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900235-7

7 January 2021

Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900235-7

7 January 2021

Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection.

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https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900235-7

7 January 2021

Phenotypic changes accompanying positive selection of CD4+CD8+ thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900235-7

7 January 2021

CD69 expression during selection and maturation of CD4+8+ thymocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900235-7

7 January 2021

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900235-7

7 January 2021

A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900235-7

7 January 2021

Rac-1 regulates nuclear factor of activated T cells (NFAT) C1 nuclear translocation in response to Fcepsilon receptor type 1 stimulation of mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900235-7

7 January 2021

Pleiotropic changes controlled by the pre-T-cell receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900235-7

7 January 2021

The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900235-7

7 January 2021

CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900235-7

7 January 2021

Requirement for the SLP-76 adaptor GADS in T cell development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900235-7

7 January 2021

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900235-7

7 January 2021

Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.

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https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900235-7

7 January 2021

10.1016/S1074-7613(01)00235-7

Identifiers

DOI

1 reference

22 April 2018

PubMed ID

11728333

1 reference

22 April 2018