(Q41429677)

30 September 2017

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title

Early alpha beta T cell development in the thymus of normal and genetically altered mice (English)

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30 September 2017

Fehling HJ

1

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30 September 2017

von Boehmer H

series ordinal

2

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30 September 2017

publication date

1 April 1997

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Current Opinion in Immunology

30 September 2017

published in

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30 September 2017

volume

9

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30 September 2017

issue

2

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30 September 2017

page(s)

263-275

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Structure and function of the pre-T cell receptor

30 September 2017

cites work

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7 January 2021

Early stages in human and mouse T-cell development

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7 January 2021

Early T lymphocyte progenitors

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7 January 2021

CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus

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7 January 2021

CD4 and CD8 expression and T cell antigen receptor gene rearrangement in early intrathymic precursor cells.

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7 January 2021

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

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7 January 2021

Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population

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7 January 2021

Thymic dendritic cell precursors: relationship to the T lymphocyte lineage and phenotype of the dendritic cell progeny

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7 January 2021

T cell receptor gene recombination patterns and mechanisms: cell death, rescue, and T cell production

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7 January 2021

T cell receptor beta chain gene rearrangement and selection during thymocyte development in adult mice

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7 January 2021

Alpha beta and gamma delta T cells can share a late common precursor

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7 January 2021

T cell receptor delta gene rearrangement and T early alpha (TEA) expression in immature alpha beta lineage thymocytes: implications for alpha beta/gamma delta lineage commitment.

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7 January 2021

Rearrangement and diversity of T cell receptor beta chain genes in thymocytes: a critical role for the beta chain in development

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7 January 2021

In transgenic mice the introduced functional T cell receptor beta gene prevents expression of endogenous beta genes

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7 January 2021

Early expression of a T-cell receptor beta-chain transgene suppresses rearrangement of the V gamma 4 gene segment

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7 January 2021

Productive T-cell receptor beta-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo.

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7 January 2021

Control points in early T-cell development

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7 January 2021

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

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7 January 2021

DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

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7 January 2021

Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.

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7 January 2021

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

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7 January 2021

Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells

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7 January 2021

A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein

1 reference

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7 January 2021

T cell receptor beta chain dimers on immature thymocytes from normal mice

1 reference

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7 January 2021

Analysis and expression of a cloned pre-T cell receptor gene

1 reference

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7 January 2021

Genomic structure and chromosomal location of the mouse pre-T-cell receptor alpha gene

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7 January 2021

Composition and function of T-cell receptor and B-cell receptor complexes on precursor lymphocytes

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7 January 2021

Early T-cell development in CD3-deficient mice.

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7 January 2021

Intra- and extra-thymic expression of the pre-T cell receptor alpha gene

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7 January 2021

Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

1 reference

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7 January 2021

Role of different T cell receptors in the development of pre-T cells.

1 reference

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7 January 2021

RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

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7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1 reference

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7 January 2021

Profound block in thymocyte development in mice lacking p56lck

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7 January 2021

An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

1 reference

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7 January 2021

Activated Ras signals differentiation and expansion of CD4+8+ thymocytes

1 reference

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7 January 2021

The regulation and function of p21ras during T-cell activation and growth.

1 reference

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7 January 2021

The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte.

1 reference

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7 January 2021

Selective requirement for MAP kinase activation in thymocyte differentiation.

1 reference

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7 January 2021

Cloning and comparative analysis of the human pre-T-cell receptor alpha-chain gene

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7 January 2021

Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilon

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7 January 2021

CD3 components at the surface of pro-T cells can mediate pre-T cell developmentin vivo

1 reference

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7 January 2021

CD3 epsilon-mediated signals rescue the development of CD4+CD8+ thymocytes in RAG-2-/- mice in the absence of TCR beta chain expression.

1 reference

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7 January 2021

Regulation of thymocyte development through CD3: Functional dissociation between p56lck and CD3ζ in early thymic selection

1 reference

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7 January 2021

Developmentally regulated expression of CD3 components independent of clonotypic T cell antigen receptor complexes on immature thymocytes

1 reference

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7 January 2021

Function of the pre-T-cell receptor alpha chain in T-cell development and allelic exclusion at the T-cell receptor beta locus

1 reference

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7 January 2021

T lymphocyte development in p56lck deficient mice: allelic exclusion of the TcR β locus is incomplete but thymocyte development is not restored by TcR β or TcR αβ transgenes

1 reference

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7 January 2021

Surrogate Light Chain Expression Is Required to Establish Immunoglobulin Heavy Chain Allelic Exclusion during Early B Cell Development

1 reference

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7 January 2021

alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980146-X

7 January 2021

Fyn can partially substitute for Lck in T lymphocyte development

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980146-X

7 January 2021

Gamma delta T cells promote CD4 and CD8 expression by SCID thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980146-X

7 January 2021

T cell receptor-negative thymocytes from SCID mice can be induced to enter the CD4/CD8 differentiation pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980146-X

7 January 2021

T cell receptor alpha gene rearrangement and transcription in adult thymic gamma delta cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980146-X

7 January 2021

Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980146-X

7 January 2021

p53 prevents maturation to the CD4+CD8+ stage of thymocyte differentiation in the absence of T cell receptor rearrangement.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980146-X

7 January 2021

A role for CD81 in early T cell development

1 reference

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7 January 2021

The ins and outs of the transmembrane 4 superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980146-X

7 January 2021

CD27 cooperates with the pre-T cell receptor in the regulation of murine T cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980146-X

7 January 2021

Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980146-X

7 January 2021

Pro-Thymocyte Expansion by c-kit and the Common Cytokine Receptor γ Chain Is Essential for Repertoire Formation

1 reference

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7 January 2021

Cytokine production and requirements during T-cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980146-X

7 January 2021

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980146-X

7 January 2021

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980146-X

7 January 2021

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

1 reference

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7 January 2021

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980146-X

7 January 2021

The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID

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https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980146-X

7 January 2021

Requirement for TNF-alpha and IL-1 alpha in fetal thymocyte commitment and differentiation.

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7 January 2021

10.1016/S0952-7915(97)80146-X

Identifiers

DOI

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30 September 2017

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