(Q50761050)

18 March 2018

title

The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte. (English)

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18 March 2018

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Crompton T

1

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18 March 2018

Gilmour KC

series ordinal

2

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18 March 2018

Owen MJ

series ordinal

3

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18 March 2018

language of work or name

English

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publication date

1 July 1996

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18 March 2018

published in

Cell

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18 March 2018

volume

86

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18 March 2018

page(s)

243-251

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18 March 2018

issue

2

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18 March 2018

Selective requirement for MAP kinase activation in thymocyte differentiation.

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[29] Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf

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Protein tyrosine kinase p56 lck controls allelic exclusion of T-cell receptor β-chain genes

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Involvement of the protein tyrosine kinase p56lck in T cell signaling and thymocyte development.

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Parallel signal processing among mammalian MAPKs

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Okadaic acid activates p42 mitogen-activated protein kinase (MAP kinase; ERK-2) in B-lymphocytes but inhibits rather than augments cellular proliferation: contrast with phorbol 12-myristate 13-acetate

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Endothelins stimulate tyrosine phosphorylation and activity of p42/mitogen-activated protein kinase in astrocytes.

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Coordinate regulation of pp90rsk and a distinct protein-serine/threonine kinase activity that phosphorylates recombinant pp90rsk in vitro

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

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Double-negative thymocyte subsets in CD3′ chain-deficient mice: Absence of HSA+CD44−CD25− cells

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Genetics of signal transduction in invertebrates

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Signal transduction and cell fate specification during Caenorhabditis elegans vulval development

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Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

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Receptor to nucleus signaling by prolactin and interleukin 2 via activation of latent DNA-binding factors

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A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein

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Development of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathway

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A single stem cell can recolonize an embryonic thymus, producing phenotypically distinct T-cell populations

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Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilon

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Regulation of T cell receptor (TCR)-beta locus allelic exclusion and initiation of TCR-alpha locus rearrangement in immature thymocytes by signaling through the CD3 complex

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Rearrangement and diversity of T cell receptor beta chain genes in thymocytes: a critical role for the beta chain in development.

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7 January 2021

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

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7 January 2021

Profound block in thymocyte development in mice lacking p56lck

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7 January 2021

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

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7 January 2021

RAG-1-deficient mice have no mature B and T lymphocytes

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7 January 2021

An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

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Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

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7 January 2021

The regulation and function of p21ras during T-cell activation and growth.

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7 January 2021

Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells

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7 January 2021

Involvement of growth factor receptors in the mammalian UVC response

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7 January 2021

Analysis and expression of a cloned pre-T cell receptor gene

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7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

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7 January 2021

Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.

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7 January 2021

JNK is involved in signal integration during costimulation of T lymphocytes.

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7 January 2021

T cell differentiation: control by the pre-TCR and alpha beta TCR.

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7 January 2021

T lymphocyte development in p56lck deficient mice: allelic exclusion of the TcR β locus is incomplete but thymocyte development is not restored by TcR β or TcR αβ transgenes

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7 January 2021

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Identifiers

DOI

1 reference

18 March 2018

PubMed ID

8706129

1 reference

18 March 2018