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Pak to the future
scientific article (publication date: September 1999)
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instance of
scholarly article
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review article
1 reference
stated in
Europe PubMed Central
title
Pak to the future
(English)
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author name string
S Bagrodia
series ordinal
1
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R A Cerione
series ordinal
2
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language of work or name
English
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publication date
September 1999
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published in
Trends in Cell Biology
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volume
9
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page(s)
350-5
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issue
9
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cites work
A brain serine/threonine protein kinase activated by Cdc42 and Rac1
1 reference
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7 January 2021
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Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
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7 January 2021
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inferred from DOI database lookup
Emerging from the Pak: the p21-activated protein kinase family.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
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7 January 2021
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inferred from DOI database lookup
PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
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Pheromone signalling and polarized morphogenesis in yeast
1 reference
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7 January 2021
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A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.
1 reference
stated in
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
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inferred from DOI database lookup
Genetic evidence for Pak1 autoinhibition and its release by Cdc42.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
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7 January 2021
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Identification of kinase-phosphatase signaling modules composed of p70 S6 kinase-protein phosphatase 2A (PP2A) and p21-activated kinase-PP2A.
1 reference
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reference URL
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7 January 2021
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inferred from DOI database lookup
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
1 reference
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reference URL
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7 January 2021
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Does Vav bind to F-actin through a CH domain?
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
A novel regulator of p21-activated kinases
1 reference
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https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
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7 January 2021
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inferred from DOI database lookup
alphaPix stimulates p21-activated kinase activity through exchange factor-dependent and -independent mechanisms
1 reference
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7 January 2021
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inferred from DOI database lookup
beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein
1 reference
stated in
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reference URL
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7 January 2021
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inferred from DOI database lookup
Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
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7 January 2021
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inferred from DOI database lookup
ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
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7 January 2021
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Identification of a new Pyk2 target protein with Arf-GAP activity
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A GTPase-independent mechanism of p21-activated kinase activation. Regulation by sphingosine and other biologically active lipids.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage and activation of p21-activated protein kinase gamma-PAK by CPP32 (caspase 3). Effects of autophosphorylation on activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-mediated activation of PAK2 during apoptosis: proteolytic kinase activation as a general mechanism of apoptotic signal transduction?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular mechanisms of nonmuscle myosin-II regulation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Kinases, myosin phosphatase and Rho proteins: curiouser and curiouser
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Rac and Cdc42 by integrins mediates cell spreading
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of non-muscle myosin II regulatory light chain by p21-activated kinase (gamma-PAK)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of myosin light chain kinase by p21-activated kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RAS and RAF-1 form a signalling complex with MEK-1 but not MEK-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The complexity of Raf-1 regulation
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenes, growth factors and phorbol esters regulate Raf-1 through common mechanisms
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for Pak protein kinases in Schwann cell transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PAK3 mutation in nonsyndromic X-linked mental retardation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A protein related to p21-activated kinase (PAK) that is involved in neurogenesis in the Drosophila adult central nervous system.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2899%2901618-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0962-8924(99)01618-9
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PubMed ID
10461188
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