(Q30176648)

9 June 2017

title

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck. (English)

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9 June 2017

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Lu W

1

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9 June 2017

Katz S

series ordinal

2

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9 June 2017

Gupta R

series ordinal

3

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9 June 2017

Mayer BJ

series ordinal

4

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9 June 2017

language of work or name

English

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publication date

1 February 1997

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9 June 2017

number of pages

10

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inferred from page(s)

published in

Current Biology

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9 June 2017

volume

7

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9 June 2017

issue

2

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9 June 2017

page(s)

85-94

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Modular binding domains in signal transduction proteins

9 June 2017

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The noncatalytic src homology region 2 segment of abl tyrosine kinase binds to tyrosine-phosphorylated cellular proteins with high affinity

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Structural basis for the binding of proline-rich peptides to SH3 domains

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Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

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7 January 2021

SH2 domains recognize specific phosphopeptide sequences

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7 January 2021

Identification of a ten-amino acid proline-rich SH3 binding site

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The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

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C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

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An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro

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A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos.

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Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3

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The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors

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The SH2/SH3 domain-containing protein Nck is recognized by certain anti-phospholipase C-gamma 1 monoclonal antibodies, and its phosphorylation on tyrosine is stimulated by platelet-derived growth factor and epidermal growth factor treatment

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7 January 2021

The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels

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Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins

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Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein.

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Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor

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Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

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Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells

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Binding of NCK to SOS and activation of ras-dependent gene expression

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7 January 2021

A Novel Ligand for SH3 Domains

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7 January 2021

Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

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7 January 2021

Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling

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7 January 2021

The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1

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Interaction of the Nck adapter protein with p21-activated kinase (PAK1)

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Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1

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7 January 2021

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

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Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

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7 January 2021

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7 January 2021

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7 January 2021

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

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7 January 2021

Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family

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7 January 2021

The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells. Evidence for a Pak-independent signaling pathway

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7 January 2021

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

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7 January 2021

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method

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7 January 2021

Mutagenic analysis of the roles of SH2 and SH3 domains in regulation of the Abl tyrosine kinase

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7 January 2021

10.1016/S0960-9822(06)00052-2

Identifiers

DOI

1 reference

9 June 2017

1 reference