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Modular binding domains in signal transduction proteins

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Modular binding domains in signal transduction proteins (English)

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Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60src substrate

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Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.

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The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

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A limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interaction

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Identification of Src, Fyn, Lyn, PI3K and Abl SH3 domain ligands using phage display libraries.

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Phosphatidylinositol 3-kinase p85 SH2 domain specificity defined by direct phosphopeptide/SH2 domain binding

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Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites

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In vivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinase

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A putative modular domain present in diverse signaling proteins

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Crystal structure at 2.2 A resolution of the pleckstrin homology domain from human dynamin

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An SH3 binding region in the epithelial Na+ channel (alpha rENaC) mediates its localization at the apical membrane

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Structure of the N-terminal SH3 domain of GRB2 complexed with a peptide from the guanine nucleotide releasing factor Sos.

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Identification of a ten-amino acid proline-rich SH3 binding site

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SH2 domains exhibit high-affinity binding to tyrosine-phosphorylated peptides yet also exhibit rapid dissociation and exchange

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Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho

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The GTPase dynamin binds to and is activated by a subset of SH3 domains

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A target for Src in mitosis.

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Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

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SH2 domains recognize specific phosphopeptide sequences

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Structure of the pleckstrin homology domain from beta-spectrin.

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Potassium selectivity in proteins: oxygen cage or pi in the face?

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Effects of SH2 and SH3 deletions on the functional activities of wild-type and transforming variants of c-Src

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Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide

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Binding of the Src SH2 domain to phosphopeptides is determined by residues in both the SH2 domain and the phosphopeptides

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Direct association of p110 beta phosphatidylinositol 3-kinase with p85 is mediated by an N-terminal fragment of p110 beta

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Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

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Structure of the regulatory domains of the Src-family tyrosine kinase Lck

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Three-dimensional solution structure of the pleckstrin homology domain from dynamin

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Structure and function of the SH3 domain

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A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase

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SH3 domains direct cellular localization of signaling molecules

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Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor

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Interactions between SH2 domains and tyrosine-phosphorylated platelet-derived growth factor beta-receptor sequences: analysis of kinetic parameters by a novel biosensor-based approach

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Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains

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GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit

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The PH domain: a common piece in the structural patchwork of signalling proteins

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Signal transduction and the actin cytoskeleton: the roles of MARCKS and profilin

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Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides

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G protein-coupled receptor kinases

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https://opencitations.net/index/coci/api/v1/references/10.1016/0092-8674(95)90406-9

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

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11 October 2022

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Oncogenes and signal transduction

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Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck

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11 October 2022

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Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis

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The IRS-1 signaling system

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High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides

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The stress-activated protein kinase subfamily of c-Jun kinases

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(Q29617351)

Modular binding domains in signal transduction proteins

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