(Q21983998)

English

Forkhead box E3

mammalian protein found in Mus musculus

Foxe3
forkhead box protein E3
Rinshoken cataract
dysgenetic lens

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Winged helix DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QY14

Winged helix-like DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QY14

Fork head domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Fork head domain conserved site1, protein family

1 reference

based on heuristic

inferred from protein domain or family

Fork head domain conserved site 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

determination method

2 references

DNA-binding transcription factor activity

determination method

4 references

14 February 2019

Functional analysis of FOXE3 mutations causing dominant and recessive ocular anterior segment disease

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

14 February 2019

A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

determination method

3 references

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QY14&geneProductId=UniProtKB:Q9QY14

determination method

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QY14&geneProductId=UniProtKB:Q9QY14

determination method

27 March 2018

Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QY14&geneProductId=UniProtKB:Q9QY14

determination method

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

14 February 2019

Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

biological process

regulation of transcription, DNA-templated

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

cell development

determination method

1 reference

14 February 2019

Severe defects in proliferation and differentiation of lens cells in Foxe3 null mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

positive regulation of epithelial cell proliferation

determination method

1 reference

14 February 2019

Severe defects in proliferation and differentiation of lens cells in Foxe3 null mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

transcription, DNA-templated

determination method

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QY14&geneProductId=UniProtKB:Q9QY14

determination method

camera-type eye development

determination method

1 reference

14 February 2019

Two interactive genes responsible for a new inherited cataract (RCT) in the mouse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

regulation of transcription by RNA polymerase II

determination method

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QY14&geneProductId=UniProtKB:Q9QY14

determination method

cornea development in camera-type eye

determination method

1 reference

14 February 2019

Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

positive regulation of lens epithelial cell proliferation

determination method

4 references

14 February 2019

Growth inhibition of human lens epithelial cells by short hairpin RNA in transcription factor forkhead box E3 (FOXE3)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

14 February 2019

A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

14 February 2019

Severe defects in proliferation and differentiation of lens cells in Foxe3 null mice

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

iris morphogenesis

determination method

1 reference

14 February 2019

Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

negative regulation of lens fiber cell differentiation

determination method

3 references

14 February 2019

Forkhead Foxe3 maps to the dysgenetic lens locus and is critical in lens development and differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

14 February 2019

A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

14 February 2019

Severe defects in proliferation and differentiation of lens cells in Foxe3 null mice

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

trabecular meshwork development

determination method

1 reference

14 February 2019

Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

ciliary body morphogenesis

determination method

1 reference

14 February 2019

Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

eye development

determination method

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

14 February 2019

A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

lens development in camera-type eye

determination method

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

14 February 2019

Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

anatomical structure morphogenesis

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

cell differentiation

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QY14

determination method

Fork head domain conserved site 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QY14

Fork head domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QY14

Fork head domain conserved site1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QY14

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000050445

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000050445

Sitelinks

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