(Q21984109)

http://www.ebi.ac.uk/interpro/protein/Q9CVD2

Josephin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ubiquitin interacting motif, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

cysteine-type peptidase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

1 reference

8 April 2019

An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

thiol-dependent deubiquitinase

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9CVD2&geneProductId=UniProtKB:Q9CVD2

24 April 2018

Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9CVD2&geneProductId=UniProtKB:Q9CVD2

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

thiol-dependent deubiquitinase

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

ubiquitin protein ligase binding

IBA

Lys63-specific deubiquitinase activity

Lys48-specific deubiquitinase activity

4 references

8 April 2019

Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

CK2 and GSK3 phosphorylation on S29 controls wild-type ATXN3 nuclear uptake

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

Study of subcellular localization and proteolysis of ataxin-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

Proteotoxic stress increases nuclear localization of ataxin-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

Study of subcellular localization and proteolysis of ataxin-3

mitochondrial membranes

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

1 reference

8 April 2019

Study of subcellular localization and proteolysis of ataxin-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence

nuclear inclusion body

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

6 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9CVD2&geneProductId=UniProtKB:Q9CVD2

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9CVD2&geneProductId=UniProtKB:Q9CVD2

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9CVD2&geneProductId=UniProtKB:Q9CVD2

24 April 2018

Proteotoxic stress increases nuclear localization of ataxin-3

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9CVD2&geneProductId=UniProtKB:Q9CVD2

24 April 2018

CK2 and GSK3 phosphorylation on S29 controls wild-type ATXN3 nuclear uptake

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9CVD2&geneProductId=UniProtKB:Q9CVD2

24 April 2018

Study of subcellular localization and proteolysis of ataxin-3

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9CVD2&geneProductId=UniProtKB:Q9CVD2

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

endoplasmic reticulum membrane

ISO

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

CK2 and GSK3 phosphorylation on S29 controls wild-type ATXN3 nuclear uptake

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

Study of subcellular localization and proteolysis of ataxin-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

Proteotoxic stress increases nuclear localization of ataxin-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

histone H3 deacetylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

cellular response to heat

1 reference

8 April 2019

Proteotoxic stress increases nuclear localization of ataxin-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

regulation of transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9CVD2&geneProductId=UniProtKB:Q9CVD2

ubiquitin-dependent protein catabolic process

1 reference

8 April 2019

Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

protein quality control for misfolded or incompletely synthesized proteins

1 reference

8 April 2019

Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

monoubiquitinated protein deubiquitination

1 reference

8 April 2019

Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9CVD2&geneProductId=UniProtKB:Q9CVD2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

1 reference

8 April 2019

Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

proteasome-mediated ubiquitin-dependent protein catabolic process

1 reference

8 April 2019

Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

cellular response to misfolded protein

1 reference

8 April 2019

Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

regulation of cell-substrate adhesion

3 references

14 February 2019

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

14 February 2019

Absence of ataxin-3 leads to cytoskeletal disorganization and increased cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

positive regulation of ERAD pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

protein localization to cytosolic proteasome complex involved in ERAD pathway

ISO

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

microtubule cytoskeleton organization

ISO

regulation of cell-substrate adhesion

4 references

8 April 2019

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

Absence of ataxin-3 leads to cytoskeletal disorganization and increased cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

protein deubiquitination

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9CVD2

actin cytoskeleton organization

IBA

intermediate filament cytoskeleton organization

protein K63-linked deubiquitination

protein K48-linked deubiquitination

Ubiquitin interacting motif

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9CVD2

Josephin domain

1 reference

stated in

InterPro Release 71.0