(Q21984263)

http://www.ebi.ac.uk/interpro/protein/P46684

Zinc finger C2H2-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

31 January 2018

CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46684&geneProductId=UniProtKB:P46684

DNA-binding transcription factor activity

DNA-binding transcription activator activity, RNA polymerase II-specific

2 references

10 September 2018

Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46684&geneProductId=UniProtKB:P46684

14 February 2019

Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

14 February 2019

Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

3 references

14 February 2019

Myogenic repressor I-mfa interferes with the function of Zic family proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

14 February 2019

Physical and functional interactions between Zic and Gli proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

14 February 2019

Physical and functional interactions between Zic and Gli proteins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

RNA polymerase II transcription regulatory region sequence-specific DNA binding

IBA

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

5 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46684&geneProductId=UniProtKB:P46684

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46684&geneProductId=UniProtKB:P46684

31 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46684&geneProductId=UniProtKB:P46684

31 January 2018

Myogenic repressor I-mfa interferes with the function of Zic family proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46684&geneProductId=UniProtKB:P46684

31 January 2018

Physical and functional interactions between Zic and Gli proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46684&geneProductId=UniProtKB:P46684

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

14 February 2019

Myogenic repressor I-mfa interferes with the function of Zic family proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

14 February 2019

Physical and functional interactions between Zic and Gli proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

pattern specification process

IBA

biological process

1 reference

14 February 2019

The expression of the mouse Zic1, Zic2, and Zic3 gene suggests an essential role for Zic genes in body pattern formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

skeletal system development

1 reference

14 February 2019

Physical and functional interactions between Zic and Gli proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

regulation of transcription, DNA-templated

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46684&geneProductId=UniProtKB:P46684

transcription, DNA-templated

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46684&geneProductId=UniProtKB:P46684

nervous system development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

positive regulation of transcription, DNA-templated

3 references

14 February 2019

Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

14 February 2019

Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

14 February 2019

Physical and functional interactions between Zic and Gli proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

regulation of smoothened signaling pathway

1 reference

14 February 2019

Physical and functional interactions between Zic and Gli proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

14 February 2019

A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

inner ear morphogenesis

1 reference

14 February 2019

Zic1 promotes the expansion of dorsal neural progenitors in spinal cord by inhibiting neuronal differentiation

ISS

spinal cord development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

positive regulation of protein import into nucleus

IMP

1 reference

14 February 2019

Physical and functional interactions between Zic and Gli proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

positive regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

Mouse Zic1 is involved in cerebellar development

adult walking behavior

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

transcription by RNA polymerase II

IMP

1 reference

31 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46684&geneProductId=UniProtKB:P46684

central nervous system development

3 references

14 February 2019

Mouse Zic1 is involved in cerebellar development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

14 February 2019

Zic2 controls cerebellar development in cooperation with Zic1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46684

IBA

has part(s)

Zinc finger C2H2-type

1 reference

stated in

InterPro Release 71.0