(Q21984423)

membrane protein

1 reference

inferred from GOA cell component → membrane

Protein kinase domain, protein family

1 reference

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

3 references

8 April 2019

Small GTPase RBJ mediates nuclear entrapment of MEK1/MEK2 in tumor progression

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

protein serine/threonine/tyrosine kinase activity

IPI

1 reference

8 April 2019

The ERK signaling cascade--views from different subcellular compartments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

protein tyrosine kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

MAP kinase kinase activity

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31938&geneProductId=UniProtKB:P31938

24 April 2018

Role of the nude gene in epithelial terminal differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31938&geneProductId=UniProtKB:P31938

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31938&geneProductId=UniProtKB:P31938

protein kinase activity

protein serine/threonine kinase activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

mitogen-activated protein kinase kinase kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

protein kinase activity

1 reference

8 April 2019

MAP kinase kinase activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

Role of the nude gene in epithelial terminal differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

The ERK signaling cascade--views from different subcellular compartments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

microtubule organizing center

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

The ERK signaling cascade--views from different subcellular compartments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

The ERK signaling cascade--views from different subcellular compartments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

The ERK signaling cascade--views from different subcellular compartments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31938&geneProductId=UniProtKB:P31938

4 references

8 April 2019

The ERK signaling cascade--views from different subcellular compartments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

perinuclear region of cytoplasm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

glutamatergic synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

regulation of protein phosphorylation

biological process

1 reference

14 February 2019

Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

positive regulation of Ras protein signal transduction

1 reference

8 April 2019

The protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

positive regulation of axonogenesis

1 reference

8 April 2019

B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

cerebellar cortex formation

1 reference

8 April 2019

Shp2-dependent ERK signaling is essential for induction of Bergmann glia and foliation of the cerebellum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

positive regulation of cell differentiation

1 reference

8 April 2019

The Grb2/Mek pathway represses Nanog in murine embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

regulation of stress-activated MAPK cascade

IDA

1 reference

8 April 2019

The ERK signaling cascade--views from different subcellular compartments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

epithelial cell proliferation involved in lung morphogenesis

1 reference

8 April 2019

Crucial requirement of ERK/MAPK signaling in respiratory tract development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

thyroid gland development

1 reference

8 April 2019

Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

Crucial requirement of ERK/MAPK signaling in respiratory tract development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

regulation of axon regeneration

1 reference

8 April 2019

B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

Crucial requirement of ERK/MAPK signaling in respiratory tract development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

regulation of early endosome to late endosome transport

1 reference

8 April 2019

The ERK signaling cascade--views from different subcellular compartments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

labyrinthine layer development

1 reference

8 April 2019

Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

placenta blood vessel development

IMP

1 reference

8 April 2019

Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

keratinocyte differentiation

IMP

1 reference

8 April 2019

Role of the nude gene in epithelial terminal differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

Bergmann glial cell differentiation

IMP

1 reference

8 April 2019

Shp2-dependent ERK signaling is essential for induction of Bergmann glia and foliation of the cerebellum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

peptidyl-tyrosine phosphorylation

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

regulation of Golgi inheritance

1 reference

8 April 2019

The ERK signaling cascade--views from different subcellular compartments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

regulation of mitotic cell cycle

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31938&geneProductId=UniProtKB:P31938

regulation of apoptotic process

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31938&geneProductId=UniProtKB:P31938

protein phosphorylation

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

14 February 2019

Presenilin acts as a positive regulator of basal level activity of ERK through the Raf-MEK1 signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

ERK1 and ERK2 cascade

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31938&geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

regulation of vascular associated smooth muscle contraction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

response to oxidative stress

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

positive regulation of autophagy

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

positive regulation of cell migration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

positive regulation of transcription elongation from RNA polymerase II promoter

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

negative regulation of homotypic cell-cell adhesion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

positive regulation of GTPase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

positive regulation of muscle contraction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

vesicle transport along microtubule

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

response to axon injury

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

neuron projection morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

protein heterooligomerization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

response to glucocorticoid

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

triglyceride homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

regulation of ERK1 and ERK2 cascade

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

positive regulation of ATP biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

neuron differentiation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

EphA receptors direct the differentiation of mammalian neural precursor cells through a mitogen-activated protein kinase-dependent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

stress-activated protein kinase signaling cascade

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

activation of protein kinase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

regulation of neurotransmitter receptor localization to postsynaptic specialization membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

protein phosphorylation

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

Presenilin acts as a positive regulator of basal level activity of ERK through the Raf-MEK1 signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938

serine/threonine-protein kinase, active site

has part(s)

1 reference

protein kinase domain

1 reference

protein kinase, ATP binding site

1 reference