(Q21984744)

English

Phosphoinositide-3-kinase adaptor protein 1

mammalian protein found in Mus musculus

B-cell adapter for phosphoinositide 3-kinase
B cell phosphoinositide 3-kinase adaptor
Pik3ap1
B-cell phosphoinositide 3-kinase adapter protein 1
phosphoinositide 3-kinase adapter protein 1

In more languages

edit

Statements

1 reference

25 May 2022

Toll/interleukin-1 receptor homology (TIR) domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9EQ32

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

DBB domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

phosphatidylinositol 3-kinase regulatory subunit binding

determination method

IDA

identical protein binding

1 reference

9 May 2019

Bioinformatics and cellular signaling

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EQ32

determination method

IPI

signaling receptor binding

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EQ32

determination method

IBA

phosphatidylinositol 3-kinase regulatory subunit binding

3 references

9 May 2019

Identification of BCAP-(L) as a negative regulator of the TLR signaling-induced production of IL-6 and IL-10 in macrophages by tyrosine phosphoproteomics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EQ32

9 May 2019

B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EQ32

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EQ32

1 reference

14 February 2019

B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EQ32

1 reference

9 May 2019

BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EQ32

determination method

IDA

biological process

positive regulation of phosphatidylinositol 3-kinase signaling

determination method

IMP

toll-like receptor 9 signaling pathway

determination method

IMP

positive regulation of toll-like receptor signaling pathway

1 reference

27 March 2018

Identification of BCAP-(L) as a negative regulator of the TLR signaling-induced production of IL-6 and IL-10 in macrophages by tyrosine phosphoproteomics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EQ32&geneProductId=UniProtKB:Q9EQ32

determination method

IMP

toll-like receptor 2 signaling pathway

1 reference

9 May 2019

Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EQ32

determination method

IMP

negative regulation of toll-like receptor signaling pathway

1 reference

27 March 2018

Identification of BCAP-(L) as a negative regulator of the TLR signaling-induced production of IL-6 and IL-10 in macrophages by tyrosine phosphoproteomics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EQ32&geneProductId=UniProtKB:Q9EQ32

determination method

IMP

regulation of MAPK cascade

1 reference

9 May 2019

B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EQ32

determination method

IMP

toll-like receptor 4 signaling pathway

determination method

IMP

toll-like receptor 7 signaling pathway

1 reference

9 May 2019

B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EQ32

determination method

IMP

regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

9 May 2019

B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EQ32

determination method

IMP

regulation of inflammatory response

1 reference

9 May 2019

Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EQ32

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9EQ32

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

(Q21984744)

Phosphoinositide-3-kinase adaptor protein 1

Statements

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)