(Q28591616)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

Myeloid differentiation primary response gene 88

19 January 2020

main subject

toll-like receptor

0 references

1 reference

Phosphoinositide-3-kinase adaptor protein 1

GOA release 2020-03-11

1 reference

Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Ty Troutman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Wei Hu

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Stephanie Fulenchek

3

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Tetsuo Yamazaki

4

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Tomohiro Kurosaki

5

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Chandrashekhar Pasare

7

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

J Fernando Bazan

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

0 references

publication date

20 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

19 January 2020

published in

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

109

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

273-278

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

1

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

19 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Pattern recognition receptors and inflammation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Mal connects TLR2 to PI3Kinase activation and phagocyte polarization

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

TAM receptors are pleiotropic inhibitors of the innate immune response

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Protein homology detection by HMM-HMM comparison

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

IRAK-M is a negative regulator of Toll-like receptor signaling

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

TIRAP: an adapter molecule in the Toll signaling pathway

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

The PSIPRED protein structure prediction server

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

A family of human receptors structurally related to Drosophila Toll

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Macrophages in the pathogenesis of atherosclerosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Role of TLR2-dependent inflammation in metastatic progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Myeloid PTEN promotes inflammation but impairs bactericidal activities during murine pneumococcal pneumonia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

TLR4/MyD88/PI3K interactions regulate TLR4 signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

When signaling pathways collide: positive and negative regulation of toll-like receptor signal transduction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Enhanced NK-cell development and function in BCAP-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Role of phosphoinositide 3-kinase in innate immunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Signaling pathways downstream of pattern-recognition receptors and their cross talk

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

New players in TLR-mediated innate immunity: PI3K and small Rho GTPases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Drosophila MyD88 is an adapter in the Toll signaling pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

Regulation of phagosome maturation by signals from toll-like receptors.

29 September 2017

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1118579109

Tyrosine phosphorylation of B-cell adaptor for phosphoinositide 3-kinase is required for Akt activation in response to CD19 engagement

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1118579109

Structural ties between cholesterol transport and morphogen signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1118579109

Essential immunoregulatory role for BCAP in B cell development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1118579109

Isolation of proteins that interact with the signal transduction molecule Dof and identification of a functional domain conserved between Dof and vertebrate BCAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1118579109

TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252926

PI3K-mediated negative feedback regulation of IL-12 production in DCs

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22187460

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Contribution of BCAP to maintenance of mature B cells through c-Rel

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22187460

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1118579109

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

ADS bibcode

2012PNAS..109..273T

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187460%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

2 references