(Q21984935)

Ureohydrolase domain superfamily

1 reference

Histone deacetylase 4

1 reference

Histone deacetylase, glutamine rich N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

histone deacetylases

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

NAD-dependent histone deacetylase activity (H3-K14 specific)

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

transcription corepressor activity

1 reference

14 February 2019

Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

histone deacetylase activity

IGI

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

protein deacetylase activity

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

transcription factor binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

mHDA1/HDAC5 histone deacetylase interacts with and represses MEF2A transcriptional activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

1 reference

14 February 2019

Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 references

14 February 2019

Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

Histone deacetylase inhibitor MS-275 stimulates bone formation in part by enhancing Dhx36-mediated TNAP transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

Epigenetic silencing of CD8 genes by ThPOK-mediated deacetylation during CD4 T cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

Androgen receptor corepressor-19 kDa (ARR19), a leucine-rich protein that represses the transcriptional activity of androgen receptor through recruitment of histone deacetylase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

Impaired placental trophoblast lineage differentiation in Alkbh1(-/-) mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

Nε-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes

protein kinase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

RNA polymerase II cis-regulatory region sequence-specific DNA binding

IPI

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6NZM9&geneProductId=UniProtKB:Q6NZM9

SUMO transferase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

A histone deacetylase 4/myogenin positive feedback loop coordinates denervation-dependent gene induction and suppression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming

neuromuscular junction

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

1 reference

14 February 2019

HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

A histone deacetylase 4/myogenin positive feedback loop coordinates denervation-dependent gene induction and suppression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

3 references

skeletal system development

1 reference

14 February 2019

Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

regulation of cardiac muscle contraction by calcium ion signaling

1 reference

14 February 2019

HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

negative regulation of glycolytic process

1 reference

14 February 2019

A histone deacetylase 4/myogenin positive feedback loop coordinates denervation-dependent gene induction and suppression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

regulation of transcription, DNA-templated

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6NZM9&geneProductId=UniProtKB:Q6NZM9

cellular response to tumor necrosis factor

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

negative regulation of transcription by RNA polymerase II

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

MEF2C transcription factor controls chondrocyte hypertrophy and bone development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

positive regulation of protein sumoylation

3 references

negative regulation of osteoblast differentiation

1 reference

14 February 2019

Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

transcription, DNA-templated

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6NZM9&geneProductId=UniProtKB:Q6NZM9

regulation of striated muscle cell differentiation

1 reference

14 February 2019

Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

positive regulation of transcription, DNA-templated

IGI

1 reference

14 February 2019

A histone deacetylase 4/myogenin positive feedback loop coordinates denervation-dependent gene induction and suppression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

cellular response to mechanical stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

response to denervation involved in regulation of muscle adaptation

1 reference

14 February 2019

A histone deacetylase 4/myogenin positive feedback loop coordinates denervation-dependent gene induction and suppression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.

osteoblast development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

regulation of skeletal muscle fiber development

1 reference

14 February 2019

Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

cellular response to parathyroid hormone stimulus

IGI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

negative regulation of transcription, DNA-templated

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

Androgen receptor corepressor-19 kDa (ARR19), a leucine-rich protein that represses the transcriptional activity of androgen receptor through recruitment of histone deacetylase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

positive regulation of transcription by RNA polymerase II

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

A histone deacetylase 4/myogenin positive feedback loop coordinates denervation-dependent gene induction and suppression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

chromatin organization

2 references

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9

Histone deacetylase, glutamine rich N-terminal domain

has part(s)

1 reference

Histone deacetylase domain

1 reference