(Q21985800)

English

MutS homolog 3

mammalian protein found in Mus musculus

protein repair-1
DNA mismatch repair protein Msh3
REP-3
Msh3
protein repair-3
REP-1

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

MutS, connector domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P13705

DNA mismatch repair protein MutS/MSH

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P13705

DNA mismatch repair protein MutS, core domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P13705

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P13705

DNA mismatch repair protein MutS, N-terminal domain, protein family

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P13705

DNA mismatch repair protein MutS, connector domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

DNA mismatch repair protein MutS, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

DNA mismatch repair protein MutS, core domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

DNA mismatch repair protein MutS-like, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

nucleotide binding

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

dinucleotide insertion or deletion binding

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

centromeric DNA binding

determination method

1 reference

9 May 2019

Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

single-stranded DNA binding

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

damaged DNA binding

determination method

1 reference

9 May 2019

HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

dinucleotide repeat insertion binding

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

single guanine insertion binding

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

mismatched DNA binding

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

Y-form DNA binding

determination method

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13705&geneProductId=UniProtKB:P13705

determination method

heteroduplex DNA loop binding

determination method

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13705&geneProductId=UniProtKB:P13705

determination method

double-strand/single-strand DNA junction binding

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

ATP-dependent activity, acting on DNA

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

determination method

guanine/thymine mispair binding

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

single thymine insertion binding

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

oxidized purine DNA binding

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

mismatched DNA binding

determination method

DNA insertion or deletion binding

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

mismatch repair complex

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

biological process

somatic hypermutation of immunoglobulin genes

determination method

1 reference

9 May 2019

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

cellular response to DNA damage stimulus

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

positive regulation of helicase activity

determination method

1 reference

31 January 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13705&geneProductId=UniProtKB:P13705

determination method

somatic recombination of immunoglobulin gene segments

determination method

1 reference

14 February 2019

Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

negative regulation of DNA recombination

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

DNA mismatch repair

determination method

7 references

31 January 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13705&geneProductId=UniProtKB:P13705

determination method

31 January 2018

The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13705&geneProductId=UniProtKB:P13705

determination method

31 January 2018

Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13705&geneProductId=UniProtKB:P13705

determination method

31 January 2018

The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13705&geneProductId=UniProtKB:P13705

determination method

31 January 2018

Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13705&geneProductId=UniProtKB:P13705

determination method

31 January 2018

The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13705&geneProductId=UniProtKB:P13705

determination method

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13705&geneProductId=UniProtKB:P13705

determination method

meiotic mismatch repair

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

removal of nonhomologous ends

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

DNA mismatch repair

determination method

8 references

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

9 May 2019

The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

9 May 2019

Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

9 May 2019

The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

9 May 2019

The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

9 May 2019

Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

mitotic recombination

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

reciprocal meiotic recombination

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

replication fork arrest

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13705

determination method

somatic recombination of immunoglobulin gene segments

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000140002

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000140002

ENSMUSP00000140402

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000140402

ENSMUSP00000139622

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000139622

ENSMUSP00000022220

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000022220

ENSMUSP00000139620

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000139620

ENSMUSP00000141163

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000141163

ENSMUSP00000140659

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000140659

ENSMUSP00000141158

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000141158

Sitelinks

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Wiktionary(0 entries)

Multilingual sites(0 entries)

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