(Q21985883)

http://www.ebi.ac.uk/interpro/protein/P70661

Neurogenin-3

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P70661

Myc-type, basic helix-loop-helix (bHLH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

protein dimerization activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

DNA-binding transcription factor activity

1 reference

14 February 2019

IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

transcription coactivator activity

1 reference

14 February 2019

Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

DNA-binding transcription repressor activity, RNA polymerase II-specific

4 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70661&geneProductId=UniProtKB:P70661

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70661&geneProductId=UniProtKB:P70661

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

1 reference

14 February 2019

Identification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

IPI

chromatin DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

DNA-binding transcription activator activity, RNA polymerase II-specific

4 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70661&geneProductId=UniProtKB:P70661

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70661&geneProductId=UniProtKB:P70661

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

RNA polymerase II cis-regulatory region sequence-specific DNA binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

14 February 2019

IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70661&geneProductId=UniProtKB:P70661

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

intracellular anatomical structure

TAS

2 references

5 June 2018

Neuronatin, a downstream target of BETA2/NeuroD1 in the pancreas, is involved in glucose-mediated insulin secretion

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70661&geneProductId=UniProtKB:P70661

5 June 2018

Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70661&geneProductId=UniProtKB:P70661

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

14 February 2019

Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

14 February 2019

Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

epithelial cell differentiation

1 reference

14 February 2019

Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

positive regulation of DNA-binding transcription factor activity

IMP

1 reference

14 February 2019

Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

hindbrain development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

transcription, DNA-templated

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70661&geneProductId=UniProtKB:P70661

nervous system development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

regulation of dendrite morphogenesis

1 reference

14 February 2019

Formin1 mediates the induction of dendritogenesis and synaptogenesis by neurogenin3 in mouse hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

positive regulation of cell differentiation

IGI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

spinal cord development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

forebrain development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

endocrine pancreas development

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

positive regulation of transcription by RNA polymerase II

3 references

1 reference

14 February 2019

IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70661

transcription by RNA polymerase II

1 reference

5 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70661&geneProductId=UniProtKB:P70661

regulation of transcription, DNA-templated

3 references

Myc-type, basic helix-loop-helix (bHLH) domain

1 reference

stated in

InterPro Release 71.0