Wikidata

(Q21986054)

English

LIM domain binding 1

mammalian protein found in Mus musculus

  • CLIM-2
  • LDB-1
  • LIM domain-binding factor CLIM2
  • mLdb1
  • carboxyl-terminal LIM domain-binding protein 2
  • nuclear LIM interactor
  • LIM domain-binding protein 1
  • Ldb1
In more languages
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No label defined

No description defined

Statements

molecular function
LIM domain binding
determination method or standard
ISO
IDA
IEA
IPI
7 references
retrieved
16 July 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
ISO
retrieved
16 July 2018
stated in
Interactions between LIM domains and the LIM domain-binding protein Ldb1
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
16 July 2018
stated in
A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IEA
retrieved
16 July 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IEA
retrieved
16 July 2018
stated in
Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IDA
retrieved
16 July 2018
stated in
Functional analysis of the nuclear LIM domain interactor NLI
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IDA
protein binding
determination method or standard
IPI
11 references
retrieved
14 February 2019
stated in
The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
14 February 2019
stated in
A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
14 February 2019
stated in
The Ldb1 and Ldb2 transcriptional cofactors interact with the Ste20-like kinase SLK and regulate cell migration
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
14 February 2019
stated in
Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
14 February 2019
stated in
Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
14 February 2019
stated in
LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
14 February 2019
stated in
Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
14 February 2019
stated in
ETO2 coordinates cellular proliferation and differentiation during erythropoiesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
14 February 2019
stated in
Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
14 February 2019
stated in
Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
14 February 2019
stated in
A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
LIM domain binding
determination method or standard
IBA
IDA
IEA
IPI
ISO
8 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
ISO
retrieved
9 May 2019
stated in
Interactions between LIM domains and the LIM domain-binding protein Ldb1
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
9 May 2019
stated in
A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IEA
retrieved
9 May 2019
stated in
Functional analysis of the nuclear LIM domain interactor NLI
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IDA
retrieved
9 May 2019
stated in
Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IBA
protein binding
determination method or standard
IPI
TAS
12 references
retrieved
9 May 2019
stated in
Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
TAS
retrieved
9 May 2019
stated in
A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
9 May 2019
stated in
The Ldb1 and Ldb2 transcriptional cofactors interact with the Ste20-like kinase SLK and regulate cell migration
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
9 May 2019
stated in
The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
9 May 2019
stated in
Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
9 May 2019
stated in
LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
9 May 2019
stated in
Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
9 May 2019
stated in
Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
9 May 2019
stated in
Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
9 May 2019
stated in
ETO2 coordinates cellular proliferation and differentiation during erythropoiesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
9 May 2019
stated in
Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
retrieved
9 May 2019
stated in
A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IPI
cell component
nucleus
determination method or standard
IDA
IEA
ISO
7 references
retrieved
16 July 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
ISO
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IEA
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IEA
retrieved
16 July 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IEA
retrieved
16 July 2018
stated in
Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IDA
retrieved
16 July 2018
stated in
The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IDA
retrieved
16 July 2018
stated in
SCL and associated proteins distinguish active from repressive GATA transcription factor complexes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IDA
nucleus
determination method or standard
IBA
IDA
IEA
ISO
8 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
ISO
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IEA
retrieved
9 May 2019
stated in
Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IDA
retrieved
9 May 2019
stated in
The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IDA
retrieved
9 May 2019
stated in
SCL and associated proteins distinguish active from repressive GATA transcription factor complexes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IBA
biological process
positive regulation of transcription by RNA polymerase II
determination method or standard
IGI
IEA
IMP
ISO
8 references
retrieved
16 July 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
ISO
retrieved
16 July 2018
stated in
A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IMP
retrieved
16 July 2018
stated in
Multiple functions of Ldb1 required for beta-globin activation during erythroid differentiation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IMP
retrieved
16 July 2018
stated in
LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IGI
retrieved
16 July 2018
stated in
Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IGI
retrieved
16 July 2018
stated in
A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IGI
retrieved
16 July 2018
stated in
Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IGI
retrieved
16 July 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method or standard
IEA
positive regulation of transcription by RNA polymerase II
determination method or standard
IBA
IEA
IGI
IMP
ISO
9 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
ISO
retrieved
9 May 2019
stated in
A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IMP
retrieved
9 May 2019
stated in
Multiple functions of Ldb1 required for beta-globin activation during erythroid differentiation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IMP
retrieved
9 May 2019
stated in
A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IGI
retrieved
9 May 2019
stated in
Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IGI
retrieved
9 May 2019
stated in
LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IGI
retrieved
9 May 2019
stated in
Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IGI
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method or standard
IBA

Identifiers

 
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