(Q21986887)

Succinate semialdehyde dehydrogenase

1 reference

Aldehyde dehydrogenase, N-terminal

1 reference

Aldehyde dehydrogenase, C-terminal

1 reference

Aldehyde dehydrogenase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Aldehyde dehydrogenase, glutamic acid active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Aldehyde dehydrogenase, cysteine active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

oxidoreductase activity

succinate-semialdehyde dehydrogenase [NAD(P)+] activity

2 references

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BWF0&geneProductId=UniProtKB:Q8BWF0

succinate-semialdehyde dehydrogenase (NAD+) activity

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BWF0&geneProductId=UniProtKB:Q8BWF0

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

IBA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

carboxylic acid binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

6 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BWF0&geneProductId=UniProtKB:Q8BWF0

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BWF0&geneProductId=UniProtKB:Q8BWF0

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BWF0&geneProductId=UniProtKB:Q8BWF0

31 January 2018

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BWF0&geneProductId=UniProtKB:Q8BWF0

31 January 2018

A mitochondrial protein compendium elucidates complex I disease biology

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BWF0&geneProductId=UniProtKB:Q8BWF0

31 January 2018

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BWF0&geneProductId=UniProtKB:Q8BWF0

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

A mitochondrial protein compendium elucidates complex I disease biology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

gamma-aminobutyric acid catabolic process

HDA

biological process

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

Seizure evolution and amino acid imbalances in murine succinate semialdehyde dehydrogenase (SSADH) deficiency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

galactosylceramide metabolic process

1 reference

14 February 2019

Lipid abnormalities in succinate semialdehyde dehydrogenase (Aldh5a1-/-) deficient mouse brain provide additional evidence for myelin alterations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

glutathione metabolic process

1 reference

14 February 2019

Enzymatic and metabolic evidence for a region specific mitochondrial dysfunction in brains of murine succinic semialdehyde dehydrogenase deficiency (Aldh5a1-/- mice)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

gamma-aminobutyric acid metabolic process

3 references

14 February 2019

Focal neurometabolic alterations in mice deficient for succinate semialdehyde dehydrogenase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

Increased guanidino species in murine and human succinate semialdehyde dehydrogenase (SSADH) deficiency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

14 February 2019

Succinic semialdehyde dehydrogenase deficiency: GABAB receptor-mediated function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

post-embryonic development

1 reference

14 February 2019

Therapeutic intervention in mice deficient for succinate semialdehyde dehydrogenase (gamma-hydroxybutyric aciduria)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

short-chain fatty acid metabolic process

1 reference

14 February 2019

Lipid abnormalities in succinate semialdehyde dehydrogenase (Aldh5a1-/-) deficient mouse brain provide additional evidence for myelin alterations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

neurotransmitter catabolic process

1 reference

14 February 2019

Seizure evolution and amino acid imbalances in murine succinate semialdehyde dehydrogenase (SSADH) deficiency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

glucosylceramide metabolic process

1 reference

14 February 2019

Lipid abnormalities in succinate semialdehyde dehydrogenase (Aldh5a1-/-) deficient mouse brain provide additional evidence for myelin alterations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

glutamine metabolic process

1 reference

14 February 2019

Altered cerebral glucose and acetate metabolism in succinic semialdehyde dehydrogenase-deficient mice: evidence for glial dysfunction and reduced glutamate/glutamine cycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

glucose metabolic process

1 reference

14 February 2019

Altered cerebral glucose and acetate metabolism in succinic semialdehyde dehydrogenase-deficient mice: evidence for glial dysfunction and reduced glutamate/glutamine cycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

glutamate metabolic process

1 reference

14 February 2019

Altered cerebral glucose and acetate metabolism in succinic semialdehyde dehydrogenase-deficient mice: evidence for glial dysfunction and reduced glutamate/glutamine cycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

glycerophospholipid metabolic process

1 reference

14 February 2019

Lipid abnormalities in succinate semialdehyde dehydrogenase (Aldh5a1-/-) deficient mouse brain provide additional evidence for myelin alterations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BWF0&geneProductId=UniProtKB:Q8BWF0

respiratory electron transport chain

1 reference

14 February 2019

Enzymatic and metabolic evidence for a region specific mitochondrial dysfunction in brains of murine succinic semialdehyde dehydrogenase deficiency (Aldh5a1-/- mice)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

acetate metabolic process

1 reference

14 February 2019

Altered cerebral glucose and acetate metabolism in succinic semialdehyde dehydrogenase-deficient mice: evidence for glial dysfunction and reduced glutamate/glutamine cycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BWF0

succinate metabolic process

1 reference

31 January 2018

Therapeutic intervention in mice deficient for succinate semialdehyde dehydrogenase (gamma-hydroxybutyric aciduria)

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BWF0&geneProductId=UniProtKB:Q8BWF0

glutamate decarboxylation to succinate

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BWF0&geneProductId=UniProtKB:Q8BWF0

central nervous system development

IBA

4 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BWF0&geneProductId=UniProtKB:Q8BWF0

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BWF0&geneProductId=UniProtKB:Q8BWF0

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BWF0&geneProductId=UniProtKB:Q8BWF0

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BWF0&geneProductId=UniProtKB:Q8BWF0

central nervous system development

IBA

3 references

Aldehyde dehydrogenase, glutamic acid active site

1 reference

Aldehyde dehydrogenase, cysteine active site

1 reference

Aldehyde dehydrogenase domain

1 reference